Introduction: Reactive oxygen species (ROS)-mediated inflammation plays a crucial role in
ischemic brain injury. Therefore, the activation of the nuclear erythroid 2 related protein and …

A multifunctional microRNA, miR-155, has been recently recognized as an important
modulator of numerous biological processes. In our previous in vitro studies, miR-155 was …

Stroke penumbra injury caused by excess glutamate is an important factor in determining
stroke outcome; however, several therapeutic approaches aiming to rescue the penumbra …

Stroke remains one of the most important causes of death and disability. Preclinical research
is a powerful tool for understanding the molecular and cellular response to stroke. However …

The intraluminal filament model of middle cerebral artery occlusion (MCAO) in mice and rats
has been plagued by inconsistency, owing in part to the multitude of variables requiring …

Functional recovery after stroke is associated with a remapping of neural circuits. This
reorganization is often associated with low-frequency, high-amplitude oscillations in the peri …

Theoretically, direct chemical reprogramming of somatic cells into neurons in the infarct area
represents a promising regenerative therapy for ischemic stroke. Previous studies have …

Abstract Evaluation of functional outcome is widely used across species to assess the
recovery process following various pathological conditions, including spinal cord injury …

Substance P (SP) is believed to play a role in traumatic brain injury (TBI), and the inhibition
of binding of SP to the tachykinin neurokinin-1 receptor (NK1R) using NK1R antagonists had …

Stroke is one of the leading causes of adult disability worldwide. After ischemic stroke,
damaged tissue surrounding the irreversibly damaged core of the infarct, the penumbra, is …