Chemokines and cytokines are critical for initiating and coordinating the organized and
sequential recruitment and activation of cells into Mycobacterium tuberculosis-infected …

Each microenvironment requires a specific set of regulatory elements that are finely and
constantly tuned to maintain local homeostasis. Various populations of regulatory T cells …

В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

T‐regulatory cells (Tregs) have a fundamental role in the establishment and maintenance of
peripheral tolerance. There is now compelling evidence that deficits in the numbers and/or …

The transcription factor forkhead box protein 3 (FOXP3) is an essential molecular marker of
regulatory T cell (Treg) development in different microenvironments. Tregs are cells …

Lung cancer (LC) and tuberculosis (TB) are two major global public health problems, and
the incidence of LC-TB is currently on the rise. Therefore effective clinical interventions are …

Infectious agents have intimately co-evolved with the host immune system, acquiring a
portfolio of highly sophisticated mechanisms to modulate immunity. Among the common …

Regulatory T cells (Tregs) play an essential role in immune homeostasis. In infectious
diseases Tregs may inhibit protective responses facilitating pathogen multiplication and …

Immune responses were assessed at the single-cell level in lymph nodes from children with
tuberculous lymphadenitis. Tuberculosis infection was associated with tissue remodeling of …

Abstract γδ T cells play an important role in innate immunity against infections; however, the
regulation of these cells remains largely unknown. In the present study, we show that ESAT …