The discovery of tumor-associated antigens, which are either selectively or preferentially
expressed by tumors, together with an improved insight in dendritic cell biology illustrating …

In haematological cancers, malignant cells circulate in the blood and lymphatic system. This
may make leukaemic cells easier to target by immunotherapy than in other types of cancer …

Carcinoembryonic antigen (CEA) is expressed on human colon carcinomas, is well
characterized, and continues to be a promising target for cancer immunotherapy in humans …

Objective: The development of immunotherapy for malignancy is greatly limited by the
characteristic weak antigenicity of tumors. The primary goal of this study was to circumvent …

Objective To investigate the antitumor effect of dendritic cell vaccine loaded with the human
lung cancer associated antigens. Methods The monocytes were separated f rom human …

Late endocytic compartments, containing MHC class II molecules in antigen presenting
cells, fuse to each other in order to deliver antigens to these molecules. We have shown …

Adoptive transfer of effector antigen‐specific immune cells is becoming a promising
treatment option in allogeneic transplantation, infectious diseases, cancer, and autoimmune …

Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder resulting from a
malignant transformation of the primitive HSCs. The disease is characterised by the …