Hairy root culture for mass-production of high-value secondary metabolites

S Srivastava, AK Srivastava - Critical reviews in biotechnology, 2007 - Taylor & Francis
Plant cell cultivations are being considered as an alternative to agricultural processes for
producing valuable phytochemicals. Since many of these products (secondary metabolites) …

Hairy root type plant in vitro systems as sources of bioactive substances

MI Georgiev, AI Pavlov, T Bley - Applied microbiology and biotechnology, 2007 - Springer
Abstract “Hairy root” systems, obtained by transforming plant tissues with the “natural genetic
engineer” Agrobacterium rhizogenes, have been known for more than three decades. To …

Secondary metabolism of hairy root cultures in bioreactors

Y Kim, BE Wyslouzil, PJ Weathers - In Vitro Cellular & Developmental …, 2002 - Springer
In vitro cultures are being considered as an alternative to agricultural processes for
producing valuable secondary metabolites. Most efforts that use differentiated cultures …

Sustainable bioproduction of phytochemicals by plant in vitro cultures: anticancer agents

M Wink, AW Alfermann, R Franke… - Plant Genetic …, 2005 - cambridge.org
Due to their complex structure with several chiral centres important anticancer agents are
still extracted from plants and not synthesized chemically on a commercial scale …

Effect of Different Agrobacterium rhizogenes Strains on Hairy Root Induction and Phenylpropanoid Biosynthesis in Tartary Buckwheat (Fagopyrum tataricum Gaertn)

A Thwe, M Valan Arasu, X Li, CH Park, SJ Kim… - Frontiers in …, 2016 - frontiersin.org
The development of an efficient protocol for successful hairy root induction by Agrobacterium
rhizogenes is the key step toward an in vitro culturing method for the mass production of …

Enhanced production of azadirachtin by hairy root cultures of Azadirachta indica A. Juss by elicitation and media optimization

RK Satdive, DP Fulzele, S Eapen - Journal of biotechnology, 2007 - Elsevier
Azadirachtin is one of the most potent biopesticides so far developed from a plant sources.
Influence of different culture media and elicitation on growth and production of azadirachtin …

Plant cell cultures: bioreactors for industrial production

B Ruffoni, L Pistelli, A Bertoli, L Pistelli - Bio-farms for nutraceuticals …, 2010 - Springer
The recent biotechnology boom has triggered increased interest in plant cell cultures, since
a number of firms and academic institutions investigated intensively to rise the production of …

Growth of hairy‐root cultures in various bioreactors for the production of secondary metabolites

BN Mishra, R Ranjan - Biotechnology and applied biochemistry, 2008 - Wiley Online Library
Agrobacterium rhizogenes‐mediated hairy‐root cultures are a very promising alternative to
the biotechnological exploitation of plant cell cultures. Their characteristic capacity for …

Establishment of hairy root cultures of Ammi majus

A Królicka, I Staniszewska, K Bielawski, E Maliński… - Plant Science, 2001 - Elsevier
Axenically grown Ammi majus plantlets were inoculated with seven different Agrobacterium
rhizogenes strains. Hairy root lines were established only after inoculation with the two …

Lignan accumulation in callus and Agrobacterium rhizogenes-mediated hairy root cultures of flax (Linum usitatissimum)

AMM Gabr, HB Mabrok, KZ Ghanem, M Blaut… - Plant Cell, Tissue and …, 2016 - Springer
Agrobacterium rhizogenes is gaining intensity in research to develop and produce a large
number of commercially important secondary metabolites, such as lignans. Worldwide …