How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

P Roy, M Orecchioni, K Ley - Nature Reviews Immunology, 2022 - nature.com
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

The impact of diet and lifestyle on gut microbiota and human health

MA Conlon, AR Bird - Nutrients, 2014 - mdpi.com
There is growing recognition of the role of diet and other environmental factors in modulating
the composition and metabolic activity of the human gut microbiota, which in turn can impact …

The oral microbiome in the pathophysiology of cardiovascular disease

A Tonelli, EN Lumngwena, NAB Ntusi - Nature Reviews Cardiology, 2023 - nature.com
Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

Fecal microbiota transplantation in metabolic syndrome: history, present and future

PF De Groot, MN Frissen, NC De Clercq… - Gut …, 2017 - Taylor & Francis
The history of fecal microbiota transplantation (FMT) dates back even to ancient China.
Recently, scientific studies have been looking into FMT as a promising treatment of various …

Harnessing gut microbes for mental health: getting from here to there

AJ Bruce-Keller, JM Salbaum, HR Berthoud - Biological psychiatry, 2018 - Elsevier
There has been an explosion of interest in the study of microorganisms inhabiting the
gastrointestinal tract (gut microbiota) and their impact on host health and physiology …

Modulation of the gastrointestinal microbiome with nondigestible fermentable carbohydrates to improve human health

EC Deehan, RM Duar, AM Armet… - Microbiology …, 2017 - Am Soc Microbiol
There is a clear association between the gastrointestinal (GI) microbiome and the
development of chronic noncommunicable diseases, providing a rationale for the …

[HTML][HTML] Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis

E Cremonini, E Daveri, A Mastaloudis, AM Adamo… - Redox biology, 2019 - Elsevier
The gastrointestinal (GI) tract can play a critical role in the development of pathologies
associated with overeating, overweight and obesity. We previously observed that …

Gut microbiota: from microorganisms to metabolic organ influencing obesity

RW Stephens, L Arhire, M Covasa - Obesity, 2018 - Wiley Online Library
Objective This review summarizes the current understanding of the relationship between gut
microbiota and the host as it pertains to the regulation of energy balance and obesity …

Multi-omic analysis of the microbiome and metabolome in healthy subjects reveals microbiome-dependent relationships between diet and metabolites

ZZ Tang, G Chen, Q Hong, S Huang, HM Smith… - Frontiers in …, 2019 - frontiersin.org
The human microbiome has been associated with health status, and risk of disease
development. While the etiology of microbiome-mediated disease remains to be fully …

Rescue of fructose-induced metabolic syndrome by antibiotics or faecal transplantation in a rat model of obesity

B Di Luccia, R Crescenzo, A Mazzoli, L Cigliano… - PLoS …, 2015 - journals.plos.org
A fructose-rich diet can induce metabolic syndrome, a combination of health disorders that
increases the risk of diabetes and cardiovascular diseases. Diet is also known to alter the …