Immunology of Kidney Disease

O Foresto-Neto, L Menezes-Silva… - Annual Review of …, 2024 - annualreviews.org
The immune system and the kidneys are closely related. Immune components mediate
acute kidney disease and are crucial to the progression of chronic kidney disease. Beyond …

[HTML][HTML] Type I IFN in Glomerular Disease: Scarring beyond the STING

AP Jimenez-Uribe, S Mangos, E Hahm - International Journal of …, 2024 - mdpi.com
The field of nephrology has recently directed a considerable amount of attention towards the
stimulator of interferon genes (STING) molecule since it appears to be a potent driver of …

[HTML][HTML] Predicting exacerbation of renal function by DNA methylation clock and DNA damage of urinary shedding cells: a pilot study

A Hishikawa, ES Nishimura, N Yoshimoto… - Scientific reports, 2024 - nature.com
Recent reports have shown the feasibility of measuring biological age from DNA methylation
levels in blood cells from specific regions identified by machine learning, collectively known …

Podocyte Ercc1 is indispensable for glomerular integrity

EY Hama, R Nakamichi, A Hishikawa, M Kihara… - Biochemical and …, 2024 - Elsevier
As life expectancy continues to increase, age-related kidney diseases are becoming more
prevalent. Chronic kidney disease (CKD) is not only a consequence of aging but also a …

Extracellular disposal of nuclear waste by APP: a protective mechanism impaired in Alzheimer's disease

G Dougnon, T Otsuka, Y Nakamura, A Sakai… - bioRxiv, 2024 - biorxiv.org
Although the amyloid beta (Abeta) hypothesis (1) has long been central to Alzheimer's
disease (AD) research, effective therapeutic strategies remain elusive (2, 3). Here we re …