Natural products for the prevention and treatment of cholestasis: A review

X Ma, Y Jiang, W Zhang, J Wang, R Wang… - Phytotherapy …, 2020 - Wiley Online Library
Cholestasis is a common manifestation of decreased bile flow in various liver diseases. It
results in fibrosis and even cirrhosis without proper treatment. It is believed that a wide range …

Molecular mechanism and research progress on pharmacology of traditional Chinese medicine in liver injury

HY Zhang, HL Wang, GY Zhong, JX Zhu - Pharmaceutical biology, 2018 - Taylor & Francis
Context: Liver disease is a common threat to human health, caused by a variety of factors
that damage the liver. Recent studies have shown that active ingredients (for example …

Dietary fiber from oat and rye brans ameliorate Western diet–induced body weight gain and hepatic inflammation by the modulation of short‐chain fatty acids, bile …

ZM Kundi, JCY Lee, J Pihlajamäki… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Dietary fiber (DF) induces changes in gut microbiota function and thus modulates the
gut environment. How this modulation is associated with metabolic pathways related to the …

[HTML][HTML] Anti-inflammatory effects of sweroside on LPS-induced ALI in mice via activating SIRT1

J Wang, X Cai, R Ma, D Lei, X Pan, F Wang - Inflammation, 2021 - Springer
Sweroside, as one of the main components of Swertia L. in Gentianaceae, has the effect of
clearing heat and detoxifying. In previous studies, sweroside has been reported to have anti …

Sweroside alleviated LPS-induced inflammation via SIRT1 mediating NF-κB and FOXO1 signaling pathways in RAW264. 7 cells

R Wang, Z Dong, X Lan, Z Liao, M Chen - Molecules, 2019 - mdpi.com
Pterocephalus hookeri was used as a traditional Chinese medicine for the treatment of
rheumatoid arthritis. Sweroside was a main iridoid isolated from P. hookeri. The present …

Sweroside prevents non-alcoholic steatohepatitis by suppressing activation of the NLRP3 inflammasome

G Yang, JH Jang, SW Kim, SH Han, KH Ma… - International Journal of …, 2020 - mdpi.com
Non-alcoholic steatohepatitis (NASH), a type of non-alcoholic fatty liver disease, is
characterized as steatosis and inflammation in the liver. NLRP3 inflammasome activation is …

Molecular mechanisms of hepatoprotective effect of tectorigenin against ANIT-induced cholestatic liver injury: Role of FXR and Nrf2 pathways

P Cao, J Gan, S Wu, Y Hu, B Xia, X Li, H Zeng… - Food and Chemical …, 2023 - Elsevier
Cholestatic liver injury is caused by toxic action or allergic reaction, resulting in abnormality
of bile formation and excretion. Few effective therapies have become available for the …

Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (Danio rerio) Model: Involvement of Cholinergic System and Brain Oxidative Stress

I Brinza, MAE Raey, W El-Kashak, OA Eldahshan… - Molecules, 2022 - mdpi.com
Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring
monoterpenes with glucose sugar attached to C-1 in the pyran ring. Sweroside can promote …

Protective effects of n-Butanol extract and iridoid glycosides of Veronica ciliata Fisch. Against ANIT-induced cholestatic liver injury in mice

W Hua, S Zhang, Q Lu, Y Sun, S Tan, F Chen… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Veronica ciliata Fisch. is a traditional medical
herb that present in more than 100 types of Tibetan medicine prescriptions, most of which …

The effects of natural iridoids and anthocyanins on selected parameters of liver and cardiovascular system functions

M Danielewski, A Matuszewska… - Oxidative medicine …, 2020 - Wiley Online Library
The old adage says,“you are what you eat.” And although it is a banality repeated by many
with a grain of salt, it also has quite a bit of truth in it, as the products we eat have a …