Introduction Microbial infections and resultant sepsis are leading causes of death in
hospitals, representing approximately 20% of total deaths worldwide. Despite the difficulties …

Severe infection can lead to sepsis. In sepsis, the host mounts an inappropriately large
inflammatory response in an attempt to clear the invading pathogen. This sustained high …

Background. Ferroptosis is a nonapoptotic form of programmed cell death, which may be
related to the occurrence and development of sepsis‐induced acute respiratory distress …

Antibody-based strategies have been attempted to antagonize early cytokines of sepsis, but
not yet been tried to target inducible late-acting mediators. Here, we report that the …

Septic cardiomyopathy (SCM) was an important pathological component of severe sepsis
and septic shock. N6-methyladenosine (m 6 A) modification was a common RNA …

The pathogenesis of microbial infections and sepsis is partly attributable to dysregulated
innate immune responses propagated by late-acting proinflammatory mediators such as …

The pathogenic mechanisms of bacterial infections and resultant sepsis are partly attributed
to dysregulated inflammatory responses sustained by some late-acting mediators including …

Electroacupuncture (EA) has both anti-inflammatory and cardio-protective effects. Activation
of calpain pathway is involved in several myocardiopathy. In sepsis, the role of calpain-2 …

Sepsis involves life-threatening organ dysfunction caused by a dysregulated host response
to infection. Despite three decades of efforts and multiple clinical trials, no treatment, except …

Acute lung injury is one of the most serious complications of sepsis, which is a common
critical illness in clinic. This study aims to investigate the role of caspase-3/gasdermin-E …