How has schizophrenia, a condition that significantly reduces an individual's evolutionary
fitness, remained common across generations and cultures? Numerous theories about the …

Although the dopamine hypothesis of schizophrenia explains the effects of all the available
antipsychotics in clinical use, there is an increasing need for developing new drugs for the …

Previous studies have shown mitochondrial dysfunction in schizophrenia (SZ) patients,
which may be caused by mitochondrial DNA (mtDNA) alterations. However, there are few …

Background Although ultra-high risk for schizophrenia (UHR) is related to both genetic and
environment factors, the precise pathogenesis is still unknow. To date, few studies have …

Background Postweaning is a pivotal period for brain development and individual growth.
As an important chemical used in medicines, foods and beverages, sodium citrate (SC) is …

Research on serious mental disorders, particularly psychosis, has revealed highly variable
symptom profiles and developmental trajectories prior to illness-onset. As Dante Cicchetti …

Negative symptoms and cognitive deficits play a major role in psychosis and significantly
influence the functional outcomes of patients, particularly those with a first episode of …

Abstract Cognitive Impairment Associated with Schizophrenia (CIAS) represents one of the
core dimensions of Schizophrenia Spectrum Disorders (SSD), with an important negative …

Affecting over 25 million people globally, schizophrenia is arguably the mental illness that
has the most profound adverse impact on the ability of individuals to live productive and …

Il est évident qu'il existe aujourd'hui un discours dominant sur l'étiologie de la schizophrénie
qui n'exclut pas complètement les facteurs environnementaux, mais qui met davantage …