The germinal centre B cell response to SARS-CoV-2
BJ Laidlaw, AH Ellebedy - Nature Reviews Immunology, 2022 - nature.com
The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …
cells and memory B cells capable of mediating long-term protective immunity …
Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity?
Many nations are pursuing the rollout of SARS-CoV-2 vaccines as an exit strategy from
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …
unprecedented COVID-19-related restrictions. However, the success of this strategy relies …
Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
The emergence of the SARS-CoV-2 variant of concern Omicron (Pango lineage B. 1.1. 529),
first identified in Botswana and South Africa, may compromise vaccine effectiveness and …
first identified in Botswana and South Africa, may compromise vaccine effectiveness and …
[HTML][HTML] SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection
The emergence of SARS-CoV-2 Omicron, first identified in Botswana and South Africa, may
compromise vaccine effectiveness and the ability of antibodies triggered by previous …
compromise vaccine effectiveness and the ability of antibodies triggered by previous …
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
L Pérez-Alós, JJA Armenteros, JR Madsen… - Nature …, 2022 - nature.com
SARS-CoV-2 vaccines are crucial in controlling COVID-19, but knowledge of which factors
determine waning immunity is limited. We examined antibody levels and T-cell gamma …
determine waning immunity is limited. We examined antibody levels and T-cell gamma …
Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine
Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was
introduced in the United Kingdom to accelerate population coverage with a single dose. At …
introduced in the United Kingdom to accelerate population coverage with a single dose. At …
Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom
We report that in a cohort of 45,965 adults, who were receiving either the ChAdOx1 or the
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2 …
BNT162b2 SARS-CoV-2 vaccines, in those who had no prior infection with SARS-CoV-2 …
Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection
Immune protection following either vaccination or infection with SARS-CoV-2 is thought to
decrease over time. We designed a retrospective study, conducted at Leumit Health …
decrease over time. We designed a retrospective study, conducted at Leumit Health …
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
C Bergamaschi, E Terpos, M Rosati, M Angel, J Bear… - Cell reports, 2021 - cell.com
Early responses to vaccination are important for shaping both humoral and cellular
protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to …
protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to …
Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma
O Van Oekelen, CR Gleason, S Agte, K Srivastava… - Cancer cell, 2021 - cell.com
COVID-19 mRNA vaccines are highly efficacious in preventing COVID-19 morbidity and
mortality in phase 3 clinical studies as well as in real-world settings. Emerging evidence …
mortality in phase 3 clinical studies as well as in real-world settings. Emerging evidence …