The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review
Cardiotoxicity is a relatively frequent and potentially serious side effect of traditional and
targeted cancer therapies. Both general measures and specific pharmacologic …
targeted cancer therapies. Both general measures and specific pharmacologic …
Anthracycline-induced cardiotoxicity: causes, mechanisms, and prevention
A Bhagat, ES Kleinerman - … Clinical Perspectives: Past, Present and Future, 2020 - Springer
Doxorubicin is an anthracycline and one of the more effective chemotherapy agents used in
the treatment of children, adolescents, and adults with osteosarcoma. Despite its …
the treatment of children, adolescents, and adults with osteosarcoma. Despite its …
[HTML][HTML] Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations
G Curigliano, D Lenihan, M Fradley, S Ganatra… - Annals of …, 2020 - Elsevier
Cancer and cardiovascular (CV) disease are the most prevalent diseases in the developed
world. Evidence increasingly shows that these conditions are interlinked through common …
world. Evidence increasingly shows that these conditions are interlinked through common …
[HTML][HTML] Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection
MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …
oncology patients. However, these antineoplastic treatments may also induce adverse …
Sodium-glucose co-transporter-2 inhibitors and cardiac outcomes among patients treated with anthracyclines
CA Gongora, ZD Drobni… - Heart Failure, 2022 - jacc.org
Background Sodium-glucose co-transporter-2 (SGLT2) inhibitors improve outcomes among
patients with established heart failure. Despite supportive basic science studies, there are …
patients with established heart failure. Despite supportive basic science studies, there are …
[HTML][HTML] Strategies to prevent anthracycline-induced cardiotoxicity in cancer survivors
Cancer diagnostics and therapies have improved steadily over the last few decades,
markedly increasing life expectancy for patients at all ages. However, conventional and …
markedly increasing life expectancy for patients at all ages. However, conventional and …
Inequity in cardio‐oncology: identifying disparities in cardiotoxicity and links to cardiac and cancer outcomes
Minority and underresourced communities experience disproportionately high rates of fatal
cancer and cardiovascular disease. The intersection of these disparities within the …
cancer and cardiovascular disease. The intersection of these disparities within the …
Advances in Multimodality Imaging in Cardio-Oncology: JACC State-of-the-Art Review
LA Baldassarre, S Ganatra, J Lopez-Mattei… - Journal of the American …, 2022 - jacc.org
The population of patients with cancer is rapidly expanding, and the diagnosis and
monitoring of cardiovascular complications greatly rely on imaging. Numerous advances in …
monitoring of cardiovascular complications greatly rely on imaging. Numerous advances in …
[HTML][HTML] Mechanisms of anthracycline-induced cardiotoxicity: is mitochondrial dysfunction the answer?
A Murabito, E Hirsch, A Ghigo - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Cardiac side effects are a major drawback of anticancer therapies, often requiring the use of
low and less effective doses or even discontinuation of the drug. Among all the drugs known …
low and less effective doses or even discontinuation of the drug. Among all the drugs known …
[HTML][HTML] Doxorubicin-induced acute cardiotoxicity is associated with increased oxidative stress, autophagy, and inflammation in a murine model
Drug-induced cardiotoxicity is a life-threatening side effect of doxorubicin (DOX) treatment
that impacts patient prognosis and survival. In the majority of cases, the acute clinical form …
that impacts patient prognosis and survival. In the majority of cases, the acute clinical form …