SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

The germinal centre B cell response to SARS-CoV-2

BJ Laidlaw, AH Ellebedy - Nature Reviews Immunology, 2022 - nature.com
The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …

Covid-19 vaccine effectiveness in New York state

ES Rosenberg, V Dorabawila, D Easton… - … England Journal of …, 2022 - Mass Medical Soc
Background Population-based data from the United States on the effectiveness of the three
coronavirus disease 2019 (Covid-19) vaccines currently authorized by the Food and Drug …

[PDF][PDF] Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant

Y Liu, J Liu, BA Johnson, H Xia, Z Ku, C Schindewolf… - Cell reports, 2022 - cell.com
We report that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta spike
mutation P681R plays a key role in the Alpha-to-Delta variant replacement during the …

Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated persons

SM Kissler, JR Fauver, C Mack, CG Tai… - … England Journal of …, 2021 - Mass Medical Soc
Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons | NEJM
Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn …

[PDF][PDF] SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses

AC Walls, KR Sprouse, JE Bowen, A Joshi, N Franko… - Cell, 2022 - cell.com
Although infections among vaccinated individuals lead to milder COVID-19 symptoms
relative to those in unvaccinated subjects, the specificity and durability of antibody …

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

M McCallum, AC Walls, KR Sprouse, JE Bowen… - Science, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the
emergence of variants, including the B. 1.617. 2 (Delta) variant of concern that is causing a …

Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies

Y Wang, C Liu, C Zhang, Y Wang, Q Hong, S Xu… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Delta variant is currently the dominant circulating strain in the
world. Uncovering the structural basis of the enhanced transmission and altered immune …

Generation time of the alpha and delta SARS-CoV-2 variants: an epidemiological analysis

WS Hart, E Miller, NJ Andrews, P Waight… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background In May, 2021, the delta (B. 1.617. 2) SARS-CoV-2 variant became
dominant in the UK, superseded by the omicron (B. 1.1. 529) variant in December, 2021 …

The global epidemic of the SARS-CoV-2 delta variant, key spike mutations and immune escape

D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
During the COVID-19 pandemic, SARS-CoV-2 variants have emerged and spread
worldwide. The Delta (B. 1.617. 2) variant was first reported in India in October 2020 and …