Targeted treatment for osteoarthritis: drugs and delivery system

L Mao, W Wu, M Wang, J Guo, H Li, S Zhang, J Xu… - Drug …, 2021 - Taylor & Francis
The management of osteoarthritis (OA) is a clinical challenge due to the particular avascular,
dense, and occluded tissue structure. Despite numerous clinical reports and animal studies …

Comparison of outcomes after Total knee arthroplasty involving postoperative neutral or residual mild Varus alignment: a systematic review and meta‐analysis

X Wan, Y Yang, D Wang, H Xu, C Huang… - Orthopaedic …, 2022 - Wiley Online Library
Comparing mainly clinical and functional outcomes as well as prosthesis survival with
neutral and residual mild varus alignment, we searched PubMed, Embase, Cochrane …

[HTML][HTML] Functional alignment philosophy in total knee arthroplasty–rationale and technique for the varus morphotype using a CT based robotic platform and …

J Shatrov, C Battelier, E Sappey-Marinier, S Gunst… - SICOT-J, 2022 - ncbi.nlm.nih.gov
Introduction: Alignment techniques in total knee arthroplasty (TKA) continue to evolve.
Functional alignment (FA) is a novel technique that utilizes robotic tools to deliver TKA with …

Mechanical alignment for primary TKA may change both knee phenotype and joint line obliquity without influencing clinical outcomes: a study comparing restored and …

E Sappey‐Marinier, C Batailler, J Swan… - Knee Surgery …, 2022 - Wiley Online Library
Purpose In total knee arthroplasty (TKA), knee phenotypes including joint line obliquity are
of interest regarding surgical realignment strategies. The hypothesis of this study is that …

[HTML][HTML] Impact of preoperative varus deformity on postoperative mechanical alignment and long-term results of “mechanical” aligned total knee arthroplasty

SM Oh, SI Bin, JY Kim, BS Lee, JM Kim - Orthopaedics & Traumatology …, 2019 - Elsevier
Purpose Preoperative varus deformity may affect postoperative mechanical alignment and
outcomes of total knee arthroplasty (TKA). In this study, we aimed to determine whether (1) …

[HTML][HTML] What are the causes of failure after total knee arthroplasty?

H Inui, R Yamagami, K Kono, K Kawaguchi - Journal of Joint Surgery and …, 2023 - Elsevier
Purpose This study aimed to review the causes of failure after total knee arthroplasty (TKA),
focusing on the causes of revision and persistent pain. Methods A literature search was …

Patient-specific instrumentation in total knee arthroplasty

VJ León-Muñoz, F Martínez-Martínez… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Total knee arthroplasty (TKA) is one of the most commonly performed
orthopedic procedures. During the past decade, patient-specific instrumentation (PSI) has …

Neutral or natural? Functional impact of the coronal alignment in total knee arthroplasty

E Schiffner, M Wild, B Regenbrecht… - The journal of knee …, 2019 - thieme-connect.com
Total knee arthroplasty (TKA) is a very successful procedure. The alignment in TKA has
been identified as being of importance to prevent early implant failure and patient …

Residual mild varus alignment and neutral mechanical alignment have similar outcome after total knee arthroplasty for varus osteoarthritis in five-year follow-up

Z Zhang, C Liu, Z Li, P Wu, S Hu… - The journal of knee …, 2020 - thieme-connect.com
The effect of residual varus on survival rate and function in patients with varus knee
osteoarthritis (OA) was considered an important issue for successful primary total knee …

[HTML][HTML] Effect of body mass index on postoperative mechanical alignment and long-term outcomes after total knee arthroplasty: a retrospective cohort study of 671 …

YH Lai, J Cao, ZX Li, W Feng, H Xu… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background A high body mass index (BMI) is associated with increased rates of
complications after total knee arthroplasty (TKA). However, no study has examined the effect …