Treating menopause—MHT and beyond

SR Davis, RJ Baber - Nature Reviews Endocrinology, 2022 - nature.com
Every woman who lives past midlife will experience menopause, which, by definition, is
complete cessation of ovarian function. This process might occur spontaneously (natural …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

[HTML][HTML] Critical role of estrogens on bone homeostasis in both male and female: from physiology to medical implications

E Noirrit-Esclassan, MC Valera, F Tremollieres… - International Journal of …, 2021 - mdpi.com
Bone is a multi-skilled tissue, protecting major organs, regulating calcium phosphate
balance and producing hormones. Its development during childhood determines height and …

Protective effects of estrogen on cardiovascular disease mediated by oxidative stress

D Xiang, Y Liu, S Zhou, E Zhou… - Oxidative medicine and …, 2021 - Wiley Online Library
Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

[HTML][HTML] Combined oral contraceptives and venous thromboembolism: review and perspective to mitigate the risk

L Morimont, H Haguet, JM Dogné, U Gaspard… - Frontiers in …, 2021 - frontiersin.org
Many factors must be considered and discussed with women when initiating a contraceptive
method and the risk of venous thromboembolism (VTE) is one of them. In this review, we …

[HTML][HTML] Phytoestrogens and health effects

MC Canivenc-Lavier, C Bennetau-Pelissero - Nutrients, 2023 - mdpi.com
Phytoestrogens are literally estrogenic substances of plant origin. Although these
substances are useful for plants in many aspects, their estrogenic properties are essentially …

[HTML][HTML] Estrogen receptors and endometriosis

E Chantalat, MC Valera, C Vaysse, E Noirrit… - International journal of …, 2020 - mdpi.com
Endometriosis is a frequent and chronic inflammatory disease with impacts on reproduction,
health and quality of life. This disorder is highly estrogen-dependent and the purpose of …

[HTML][HTML] Mechanisms for estrogen receptor expression in human cancer

H Hua, H Zhang, Q Kong, Y Jiang - Experimental hematology & oncology, 2018 - Springer
Estrogen is a steroid hormone that has critical roles in reproductive development, bone
homeostasis, cardiovascular remodeling and brain functions. However, estrogen also …

Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms

ER Drury, J Wu, JC Gigliotti, TH Le - Physiological Reviews, 2024 - journals.physiology.org
The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …