Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics
Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
[HTML][HTML] Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …
Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …
dramatic developments over the past decade. This review focuses on state of the art in LC …
[HTML][HTML] Toward building mass spectrometry-based metabolomics and lipidomics atlases for biological and clinical research
Current metabolomics and lipidomics studies are limited in the number of examined
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …
matrices, the breadth and scope of methods, reporting the number of metabolites, and data …
Objective set of criteria for optimization of sample preparation procedures for ultra-high throughput untargeted blood plasma lipid profiling by ultra performance liquid …
Exploratory or untargeted ultra performance liquid chromatography–mass spectrometry
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …
Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry
J Zhou, Y Yin - Analyst, 2016 - pubs.rsc.org
Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical
strategies have brought about great progress in targeted metabolomics analysis. This …
strategies have brought about great progress in targeted metabolomics analysis. This …
Applications of NMR spectroscopy to systems biochemistry
TWM Fan, AN Lane - Progress in nuclear magnetic resonance spectroscopy, 2016 - Elsevier
The past decades of advancements in NMR have made it a very powerful tool for metabolic
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …
[HTML][HTML] Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and …
K Contrepois, L Jiang, M Snyder - Molecular & Cellular Proteomics, 2015 - ASBMB
Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health
and disease and for providing insights into human physiology. Since human urine and …
and disease and for providing insights into human physiology. Since human urine and …
Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial
J Pezzatti, J Boccard, S Codesido, Y Gagnebin… - Analytica chimica …, 2020 - Elsevier
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …
changes taking place in biological systems under different conditions. By its nature, this is a …
B cell activity is impaired in human and mouse obesity and is responsive to an essential fatty acid upon murine influenza infection
R Kosaraju, W Guesdon, MJ Crouch… - The Journal of …, 2017 - journals.aai.org
Obesity is associated with increased risk for infections and poor responses to vaccinations,
which may be due to compromised B cell function. However, there is limited information …
which may be due to compromised B cell function. However, there is limited information …