Early mechanistic events induced by low molecular weight polycyclic aromatic hydrocarbons in mouse lung epithelial cells: a role for eicosanoid signaling

KJ Siegrist, DD Romo, BL Upham… - Toxicological …, 2019 - academic.oup.com
Low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs;< 206.3 g/mol) are
under regulated environmental contaminants (eg, secondhand smoke) that lead to gap …

Multi-omics analysis of lung tissue demonstrates changes to lipid metabolism during allergic sensitization in mice

KN Turi, CR Michel, J Manke, KA Doenges… - Metabolites, 2023 - mdpi.com
Allergy and asthma pathogenesis are associated with the dysregulation of metabolic
pathways. To understand the effects of allergen sensitization on metabolic pathways, we …

Analytical strategies to profile the internal chemical exposome and the metabolome of human placenta

R Al-Salhi, C Monfort, N Bonvallot, A David - Analytica Chimica Acta, 2022 - Elsevier
As a non-invasive biological matrix, the placenta offers great and novel opportunities to
monitor fetal exposure to exogenous chemicals and their biotransformation products (the …

Metabolomic similarities between bronchoalveolar lavage fluid and plasma in humans and mice

C Cruickshank-Quinn, R Powell, S Jacobson… - Scientific reports, 2017 - nature.com
This observational study catalogues the overlap in metabolites between matched
bronchoalveolar lavage fluid (BALF) and plasma, identifies the degree of congruence …

Development of an UHPLC-diode arrays detector (DAD) method for the analysis of polydatin in human plasma

S Montanari, L Davani, V Tumiatti, M Dimilta… - … of Pharmaceutical and …, 2021 - Elsevier
A new chromatographic method by Ultra High Performance Liquid Chromatographic
(UHPLC) technology, has been developed and validated for the determination of polydatin …

[HTML][HTML] An automated online three-phase electro-extraction setup with machine-vision process monitoring hyphenated to LC-MS analysis

Y He, P Miggiels, N Drouin, PW Lindenburg… - Analytica Chimica …, 2022 - Elsevier
Sample preparation is a labor-intensive and time-consuming procedure, especially for the
bioanalysis of small-volume samples with low-abundant analytes. To minimize losses and …

Integration of untargeted and pseudotargeted metabolomics for authentication of three shrimp species using UHPLC-Q-Orbitrap

P Zhong, X Wei, Y Xu, L Zhang, A Koidis… - Journal of agricultural …, 2021 - ACS Publications
In this work, an untargeted and pseudotargeted metabolomics combination approach was
used for authentication of three shrimp species (Litopenaeus vanmamei, Penaeus …

[HTML][HTML] Automated preparation of plasma lipids, metabolites, and proteins for LC/MS-based analysis of a high-fat diet in mice

N Vu, TM Maile, S Gollapudi, A Gaun, P Seitzer… - Journal of Lipid …, 2024 - Elsevier
Blood plasma is one of the most commonly analyzed and easily accessible biological
samples. Here, we describe an automated liquid-liquid extraction (LLE) platform that …

A new metabolomics-based strategy for identification of endogenous markers of urine adulteration attempts exemplified for potassium nitrite

AE Steuer, K Arnold, TD Schneider, M Poetzsch… - Analytical and …, 2017 - Springer
Urine adulteration to circumvent positive drug testing represents a problem for toxicological
laboratories. While creatinine is a suitable marker for dilution, detection of chemicals is often …

Choosing an Optimal Sample Preparation in Caulobacter crescentus for Untargeted Metabolomics Approaches

J Pezzatti, M Bergé, J Boccard, S Codesido… - Metabolites, 2019 - mdpi.com
Untargeted metabolomics aims to provide a global picture of the metabolites present in the
system under study. To this end, making a careful choice of sample preparation is …