[HTML][HTML] Therapeutic potential of natural alkaloid emetine against emerging COVID-19 and future viral pandemics
B Dinda, S Dinda, M Dinda, IS Sarma… - European Journal of …, 2024 - Elsevier
The outbreak of COVID-19 pandemic caused by the infection of SARS-CoV-2, has become a
global crisis, threatening public health and disrupting global economy. Until now, effective …
global crisis, threatening public health and disrupting global economy. Until now, effective …
[HTML][HTML] Endocytosis inhibitors block SARS-CoV-2 pseudoparticle infection of mink lung epithelium
Introduction Both spill over and spill back of SARS-CoV-2 virus have been reported on mink
farms in Europe and the United States. Zoonosis is a public health concern as dangerous …
farms in Europe and the United States. Zoonosis is a public health concern as dangerous …
[HTML][HTML] Психоневрологические расстройства у пациентов с новой коронавирусной инфекцией как мультидисциплинарная проблема
АБ Шмуклер - Социальная и клиническая психиатрия, 2021 - cyberleninka.ru
В обзоре литературы представлен анализ патогенетических механизмов
психиатрических и неврологических расстройств, связанных с новой коронавирусной …
психиатрических и неврологических расстройств, связанных с новой коронавирусной …
Tissue‐and cell‐expression of druggable host proteins provide insights into repurposing drugs for COVID‐19
J Li, Y Xue, X Wang, LS Smith, B He… - Clinical and …, 2022 - Wiley Online Library
Several human host proteins play important roles in the lifecycle of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2). Many drugs targeting these host proteins have …
syndrome coronavirus 2 (SARS‐CoV‐2). Many drugs targeting these host proteins have …
[HTML][HTML] Spectroscopic studies under properties of chlorpromazine conjugated to gold nanoparticles
P Gnacek, N Piergies, P Niemiec, O Kowalska… - … Acta Part A: Molecular …, 2024 - Elsevier
Scientific studies have demonstrated that conjugates of anticancer drugs with metal
nanoparticles (MeNPs) lead to a more effective deactivation of tumor cells compared to free …
nanoparticles (MeNPs) lead to a more effective deactivation of tumor cells compared to free …
[HTML][HTML] Using Mesoporous Silica-Based Dual Biomimetic Nano-Erythrocytes for an Improved Antitumor Effect
Z Xi, Y Jiang, Z Ma, Q Li, X Xi, C Fan, S Zhu, J Zhang… - Pharmaceutics, 2023 - mdpi.com
The nano-delivery system with a dual biomimetic effect can penetrate deeper in tumor
microenvironments (TMEs) and release sufficient antitumor drugs, which has attracted much …
microenvironments (TMEs) and release sufficient antitumor drugs, which has attracted much …
Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19?
Several studies have reported that certain psychoactive drugs could have a protective effect
against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic …
against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic …
[HTML][HTML] G4-binding drugs, chlorpromazine and prochlorperazine, repurposed against COVID-19 infection in hamsters
SS Roy, S Sharma, ZA Rizvi, D Sinha… - Frontiers in Molecular …, 2023 - frontiersin.org
The COVID-19 pandemic caused by SARS-CoV-2 has caused millions of infections and
deaths worldwide. Limited treatment options and the threat from emerging variants underline …
deaths worldwide. Limited treatment options and the threat from emerging variants underline …
[HTML][HTML] Kite-shaped molecules block SARS-CoV-2 cell entry at a post-attachment step
SW Chan, T Shafi, RC Ford - Viruses, 2021 - mdpi.com
Anti-viral small molecules are currently lacking for treating coronavirus infection. The long
development timescales for such drugs are a major problem, but could be shortened by …
development timescales for such drugs are a major problem, but could be shortened by …
[HTML][HTML] Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex
Y Feng, S Grotegut, P Jovanovic, V Gandin… - Frontiers in …, 2022 - frontiersin.org
The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis.
Alterations in eIF4F activity are linked to several diseases, including cancer and infectious …
Alterations in eIF4F activity are linked to several diseases, including cancer and infectious …