Available drugs and supplements for rapid deployment for treatment of COVID-19
D Cicka, VP Sukhatme - Journal of molecular cell biology, 2021 - academic.oup.com
Materials and methods Coronaviruses are classified into four genera: α, β, γ, and δ. All
seven coronaviruses known to cause respiratory infections in humans fall into the α or β …
seven coronaviruses known to cause respiratory infections in humans fall into the α or β …
Sigma-1 Receptor Ligands Chlorpromazine and Trifluoperazine Attenuate Ca2+ Responses in Rat Peritoneal Macrophages
LS Milenina, ZI Krutetskaya, VG Antonov… - Cell and Tissue …, 2022 - Springer
Sigma-1 receptors are ubiquitous multifunctional ligand-regulated molecular chaperones in
the endoplasmic reticulum membrane with a unique history, structure, and pharmacological …
the endoplasmic reticulum membrane with a unique history, structure, and pharmacological …
[HTML][HTML] 吩噻嗪类化合物潜在抗冠状病毒活性的研究进展
万君玥, 陈华, 尹婕 - 药学学报, 2020 - html.rhhz.net
冠状病毒(coronaviruses, CoVs) 与哺乳类动物的多种疾病的产生有关, 近年来造成了多起人类
呼吸系统传染病的暴发. 目前为止还没有相关治疗药物或疫苗被批准用于治疗冠状病毒 …
呼吸系统传染病的暴发. 目前为止还没有相关治疗药物或疫苗被批准用于治疗冠状病毒 …
Unraveling the role of autophagy regulation in Crohn's disease: from genetic mechanisms to potential therapeutics
Z Yuan, J Ye, B Liu, L Zhang - Advanced Biotechnology, 2024 - Springer
Autophagy serves as the primary intracellular degradation mechanism in which damaged
organelles and self-cytoplasmic proteins are transported to the lysosome for degradation …
organelles and self-cytoplasmic proteins are transported to the lysosome for degradation …
Cholesterol and ceramide facilitate SARS-CoV-2 Spike protein-mediated membrane fusion
K Niort, J Dancourt, E Boedec, ZA Amir Dache… - bioRxiv, 2022 - biorxiv.org
SARS-CoV-2 entry into host cells is mediated by the Spike (S) protein of the viral envelope.
The S protein is composed of two subunits: S1 that induces binding to the host cell via its …
The S protein is composed of two subunits: S1 that induces binding to the host cell via its …
Comprehensive elucidation of small molecule therapeutic behavior using multitarget theory
W Mangione - 2022 - search.proquest.com
The ability to accurately determine therapeutic and adverse effects of drugs using
computational means would significantly reduce the failure rate of novel therapeutics in the …
computational means would significantly reduce the failure rate of novel therapeutics in the …
Regulation of the proteostasis network during enterovirus infection: A feedforward mechanism for EV-A71 and EV-D68
The proteostasis network guarantees successful protein synthesis, folding, transportation,
and degradation. Mounting evidence has revealed that this network maintains proteome …
and degradation. Mounting evidence has revealed that this network maintains proteome …
The cellular entry mechanism and potential target of the novel bioactive peptide AFYRW derived from Fagopyrum tataricum
J Zuo, Y Jiang, C Wang, Y Xiao, J Yang, Y Deng… - 2023 - researchsquare.com
The novel bioactive peptide AFYRW derived from Tartary buckwheat (Fagopyrum tataricum
Gaertn.) with strong antioxidant capacity was identified in our previous research, but its …
Gaertn.) with strong antioxidant capacity was identified in our previous research, but its …
[PDF][PDF] provide insights into repurposing drugs for COVID-19
J Li, Y Xue, X Wang, LS Smith, B He, S Liu, HJ Zhu - 2022 - scienceopen.com
Several human host proteins play important roles in the lifecycle of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Many drugs targeting these host proteins have …
syndrome coronavirus 2 (SARS-CoV-2). Many drugs targeting these host proteins have …
Mécanismes d'entrée de SARS-CoV-2: relation hôte-virus au site de primo-infection et repositionnement thérapeutique
M Morin-Dewaële - 2023 - theses.hal.science
Un projet de repositionnement thérapeutique a été développé avec le Prof. S. Jamain
(Institut Mondor de Recherche Biomédicale, Equipe 15), basé sur l'absence de patients …
(Institut Mondor de Recherche Biomédicale, Equipe 15), basé sur l'absence de patients …