Background The remarkable growth of genome-wide association studies (GWAS) has
created a critical need to experimentally validate the disease-associated variants, 90% of …

A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …

Mechanical stimulation plays an important role in bone remodeling. Exercise-induced
mechanical loading enhances bone strength, whereas mechanical unloading leads to bone …

As a common malignant tumor among women, ovarian cancer poses a serious threat to their
health. This study demonstrates that long non-coding RNA NRSN2-AS1 is over-expressed …

Osteoporosis (OP) is characterized by a decrease in osteoblasts and an increase in
adipocytes in the bone marrow compartment, alongside abnormal bone/fat differentiation …

Osteomyelitis, a debilitating bone infection, presents considerable clinical challenges due to
its intricate etiology and limited treatment options. Despite strides in surgical and …

Orthodontic tooth movement relies on bone remodeling and periodontal tissue regeneration
in response to the complicated mechanical cues on the compressive and tensive side. In …

Objectives In recent years, long non‐coding RNAs (lncRNAs) have been found to play a role
in the occurrence, progression and prognosis of chronic musculoskeletal disorders. Design …

Objective Long non-coding RNA plays an important role in osteogenic differentiation.
Nuclear enriched abundant transcript 1 (NEAT1) has been revealed to promote osteogenic …

Osteoporosis is a common metabolic bone disorder typically characterized by decreased
bone mass and an increased risk of fracture. At present, the detailed molecular mechanism …