Hypertension is associated with immune cells activation and their migration into the kidney,
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …

A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

Chemokines exert crucial roles in inducing immune responses through ligation to their
canonical receptors. Besides these receptors, there are other atypical chemokine receptors …

A large number of investigations have demonstrated the participation of the immune system
in the pathogenesis of hypertension. Studies focusing on macrophages and Toll-like …

Over the last few years, evidence has accumulated to suggest that hypertension is, at least
in part, an immune‐mediated inflammatory disorder. Many links between immunity and …

Hypertension is a major risk factor for cardiovascular disease, which is a serious health
problem in the highly industrialized countries. In more than 95% of the cases, the etiology of …

Immune cells infiltrate the kidney, vasculature, and central nervous system during
hypertension, consequently amplifying tissue damage and/or blood pressure elevation …

Curcumin, as a vegetative flavonoid, has a protective and therapeutic role in various
adverse states such as oxidative stress and inflammation. Remedial properties of this …

Inappropriate activation of the renin angiotensin system (RAS) is a key contributor to the
pathogenesis of essential hypertension. During RAS activation, infiltration of immune cells …

Essential hypertension is idiopathic although it is accepted as a complex polygenic trait with
underlying genetic components, which remain unknown. Our supposition is that primary …