Heavily calcified lesions may be difficult to dilate adequately with conventional balloons and
stents, which causes frequent periprocedural complications and higher rates of target lesion …

Vascular aging, early vascular aging or supernormal vascular aging are concepts used for
estimating the cardiovascular risk at a certain age. From the famous line of Thomas …

Purpose: To evaluate the safety and feasibility of treating calcified infrapopliteal stenoses
using an intravascular lithotripsy (IVL) system. Methods: The Disrupt BTK study was a …

Specific patient cohorts are at increased risk of vascular calcification. Functional matrix-gla
protein (MGP), a tissue-derived vitamin K dependent protein, is reported to be an important …

Medial artery calcification (MAC) is a distinct, highly regulated process that is often identified
in small and mid-sized arteries of the lower extremities. It is associated with advanced age …

Heparan sulphate (HS) can act as a co-receptor on the cell surface and alterations in this
process underpin many pathological conditions. We have previously described the …

Purpose To summarize the 5-year outcomes of drug-coated balloon (DCB) for the treatment
of femoropopliteal lesions in patients with diabetes mellitus (DM) or chronic limb-threatening …

Lower limb arterial calcification (LLAC) is associated with an increased risk of mortality and it
predicts poor outcomes after endovascular interventions in patients with peripheral artery …

Background Evidence of adverse clinical outcomes for non-vitamin K antagonist oral
anticoagulant (NOACs) and warfarin in patients with atrial fibrillation (AF) and diabetes …

Purpose: To investigate the prognostic impact of infrapopliteal (IP) artery anatomic severity
according to the Global Limb Anatomic Staging System (GLASS) on delayed wound healing …