The design of bioisosteres represents a creative and productive approach to improve a
molecule, including by enhancing potency, addressing pharmacokinetic challenges …

To ensure ongoing sustainability, the modern agrochemical industry is faced with enormous
challenges. These arise from provision of high‐quality food to increasing water use and …

Developing environmentally friendly fungicides is crucial to tackle the issue of rising
pesticide resistance. In this study, a series of novel pyrazole-4-carboxamide derivatives …

Lead discovery and molecular target identification are important for developing novel
pesticides. Scaffold hopping, an effective approach of modern medicinal and agrochemical …

A series of novel pyrazole-4-carboxamides bearing an ether group were designed and
synthesized on the basis of the structure of commercial succinate dehydrogenase inhibitor …

To develop novel succinate dehydrogenase inhibitors (SDHIs), two series of novel N-4-
fluoro-pyrazol-5-yl-benzamide and N-4-chloro-pyrazol-5-yl-benzamide derivatives were …

New mixed ligand complexes with metal ions (Ni (II), Co (II), Zn (II), and Fe (III)) of the type
[ML 1 L 2](where L 1= indoline-2, 3-dione and L 2= naphthalene-1, 2-dione) were …

Succinate dehydrogenase (SDH) inhibitor is one of the research hotspots for the
development of fungicides. Herein, we describe the design and synthesis of N-methoxy …

β-Methoxyacrylate derivatives represent a new class of pesticides, which have attracted
increasing attention owing to their unique structure, broad biological activity, and unique …

The conformational restriction switch concept has been adopted as a major tool for structural
optimization of pharmaceuticals in order to expand the chemical structure scope and …