Men diagnosed with low-to intermediate-risk, clinically localized prostate cancer (PCa) often
face a daunting and difficult decision with respect to treatment: active surveillance (AS) or …

Prostate cancer is the most common cancer (other than skin cancer) in American men, with
one in seven men being diagnosed with this disease during his lifetime. The estimated …

Context The great controversy surrounding the treatment of localized prostate cancer is
related with its possibilities of radical treatment or active surveillance. The objective of this …

Focal laser ablation destroys cancerous cells via thermal destruction of tissue by a laser.
Heat is absorbed, causing thermal necrosis of the target region. It combines the aggressive …

Laser focal therapy (LFT) is an evolving ablative technique for the treatment of prostate
cancer. Also referred to as laser interstitial thermal therapy (LITT) or focal laser ablation …

Objectives To evaluate utility of T2*-weighted (T2* W) MRI as a tool for intra-operative
identification of ablation zone extent during focal laser ablation (FLA) of prostate cancer …

Diffuse optical tomography in a transrectal configuration (TR-DOT) has been developed to
monitor progression of the photocoagulation front during interstitial photothermal therapy …

Background Approximately, 240,000 men in the US are diagnosed with prostate cancer
annually [1]. The majority of these cases represent low-risk, organ-confined disease for …

Introduction: To develop and evaluate a technique of 3.0 Tesla magnetic resonance (MR)
guided laser ablation based on 3-dimentional mapping biopsy (3DMB) for low risk prostate …

Minimally invasive targeted therapy has steadily developed into an integral part of cancer
treatment paradigms over the last 2 decades. The urologic oncology community has …