Systemic lupus erythematosus (SLE) is a devastating autoimmune disease that can result in
substantial morbidity and mortality. Diagnosis and treatment of SLE are clinical challenges …

Systemic lupus erythematosus (SLE) is a genetically predisposed, female-predominant
disease, characterized by multiple organ damage, that in its most severe forms can be life …

Objectives To update the EULAR recommendations for the management of systemic lupus
erythematosus (SLE) based on emerging new evidence. Methods An international Task …

Objectives To assess the associations of severe non‐adherence to HCQ, objectively
assessed by HCQ serum levels, and risks of SLE flares, damage, and mortality over 5 years …

Plasmacytoid dendritic cells (pDCs) are a professional type I IFN producer that play critical
roles in the pathogenesis of autoimmune diseases. However, both genetic regulation of the …

Methods| We identified patients with SLE from Massachusetts General Hospital who had 2
or more rheumatology visits and used hydroxychloroquine between January 1, 2016, and …

Background: Hydroxychloroquine is recommended for all patients with systemic lupus
erythematosus and is often used for other inflammatory conditions, but a critical long-term …

Systemic lupus erythematosus (SLE) is a severe multisystem autoimmune disease that can
cause injury in almost every body system. While considered a classic example of …

Background Recent guidelines for SLE recommend using a hydroxychloroquine (HCQ)
dose less than 5.0 mg/kg/day to reduce the risk of retinopathy. To determine if this dose …

Системная красная волчанка (СКВ)-системное аутоиммунное ревматическое
заболевание неизвестной этиологии, характеризующееся гиперпродукцией …