VLDL Biogenesis and Secretion: it takes a village
W Van Zwol, B Van De Sluis, HN Ginsberg… - Circulation …, 2024 - Am Heart Assoc
The production and secretion of VLDLs (very-low-density lipoproteins) by hepatocytes has a
direct impact on liver fat content, as well as the concentrations of cholesterol and …
direct impact on liver fat content, as well as the concentrations of cholesterol and …
OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression
S Yang, J Zhang, Y Xu, J Wang, H Zhao, J Lei… - Cancer Immunology …, 2022 - Springer
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related
mortality; however, effective immunotherapy strategies are limited because of the …
mortality; however, effective immunotherapy strategies are limited because of the …
LZP is required for hepatic triacylglycerol transportation through maintaining apolipoprotein B stability
JX Wu, KY He, ZZ Zhang, YL Qu, XB Su, Y Shi… - PLoS …, 2021 - journals.plos.org
The conserved zona pellucida (ZP) domain is found in hundreds of extracellular proteins
that are expressed in various organs and play a variety of roles as structural components …
that are expressed in various organs and play a variety of roles as structural components …
OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis via regulating the arachidonic acid metabolism
J Wen, A Aili, YX Yan, YL Lai, S Niu, S He… - Frontiers in …, 2022 - frontiersin.org
Background Oncoprotein-Induced Transcript 3 Protein (OIT3) was identified as a liver-
specific gene with abnormal expression in hepatocellular carcinoma (HCC). Herein, we …
specific gene with abnormal expression in hepatocellular carcinoma (HCC). Herein, we …
[HTML][HTML] OIT3 deficiency impairs uric acid reabsorption in renal tubule
B Yan, ZZ Zhang, LY Huang, HL Shen, ZG Han - FEBS letters, 2012 - Elsevier
The oncoprotein induced transcript 3 (OIT3), also named liver-specific zona pellucida
domain-containing protein (LZP), has been shown to be expressed in kidney, and was …
domain-containing protein (LZP), has been shown to be expressed in kidney, and was …
Liver-specific ZP domain-containing protein (LZP) as a new partner of Tamm-Horsfall protein harbors on renal tubules
Liver-specific ZP domain-containing protein (LZP) was recently identified as a secreted
protein that is specifically expressed in liver. However, the physiological effects of LZP are …
protein that is specifically expressed in liver. However, the physiological effects of LZP are …
[HTML][HTML] Gout inheritance in an extended Chinese family analyzed by whole-exome sequencing: A case-report
P Yang, X Pi, TN Marion, J Wang, G Wang, Y Xie… - Medicine, 2020 - journals.lww.com
Interventions: Six direct descendants and 3 healthy spouses in 1 family were recruited in our
study. Whole-exome sequencing was conducted in all participants. Outcomes: Whole …
study. Whole-exome sequencing was conducted in all participants. Outcomes: Whole …