[HTML][HTML] Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …
public health burden worldwide. The most common form of NCD is metabolic diseases …
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic
liver disease globally and is currently estimated to affect up to 38% of the global adult …
liver disease globally and is currently estimated to affect up to 38% of the global adult …
A phase 2 randomized trial of survodutide in MASH and fibrosis
AJ Sanyal, P Bedossa, M Fraessdorf… - … England Journal of …, 2024 - Mass Medical Soc
Background Dual agonism of glucagon receptor and glucagon-like peptide-1 (GLP-1)
receptor may be more effective than GLP-1 receptor agonism alone for treating metabolic …
receptor may be more effective than GLP-1 receptor agonism alone for treating metabolic …
Gastrointestinal cancers in lean individuals with non‐alcoholic fatty liver disease: a systematic review and meta‐analysis
Abstract Background & Aims Obesity and non‐alcoholic fatty liver disease (NAFLD) are
known risk factors for gastrointestinal (GI) cancers. However, GI carcinogenesis in lean …
known risk factors for gastrointestinal (GI) cancers. However, GI carcinogenesis in lean …
Implications of the new nomenclature of steatotic liver disease and definition of metabolic dysfunction‐associated steatotic liver disease
Summary Background The American and European liver associations have endorsed new
nomenclature of steatotic liver disease (SLD) and definition of metabolic dysfunction …
nomenclature of steatotic liver disease (SLD) and definition of metabolic dysfunction …
[HTML][HTML] Steatotic liver disease, MASLD and risk of chronic kidney disease
With the rising tide of fatty liver disease related to metabolic dysfunction worldwide, the
association of this common liver disease with chronic kidney disease (CKD) has become …
association of this common liver disease with chronic kidney disease (CKD) has become …
[HTML][HTML] Latest advances in hepatocellular carcinoma management and prevention through advanced technologies
TA Addissouky, IETE Sayed, MMA Ali, Y Wang… - Egyptian Liver …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) is a common type of liver cancer, with a high
mortality rate. Hepatocellular carcinoma is a type of liver cancer that can be effectively …
mortality rate. Hepatocellular carcinoma is a type of liver cancer that can be effectively …
NAFLD and NASH: etiology, targets and emerging therapies
S Wei, L Wang, PC Evans, S Xu - Drug Discovery Today, 2024 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) pose a
significant threat to human health and cause a tremendous socioeconomic burden …
significant threat to human health and cause a tremendous socioeconomic burden …
[HTML][HTML] Unmasking the enigma of lipid metabolism in metabolic dysfunction-associated steatotic liver disease: from mechanism to the clinic
G Rao, X Peng, X Li, K An, H He, X Fu, S Li… - Frontiers in Medicine, 2023 - frontiersin.org
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly defined as non-
alcoholic fatty liver disease (NAFLD), is a disorder marked by the excessive deposition of …
alcoholic fatty liver disease (NAFLD), is a disorder marked by the excessive deposition of …
[HTML][HTML] Management of cardiovascular risk in patients with metabolic dysfunction-associated steatotic liver disease
A Mellemkjær, MB Kjær, D Haldrup, H Grønbæk… - European Journal of …, 2023 - Elsevier
Abstract The novel term Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
is proposed to replace non-alcoholic fatty liver disease (NAFLD) to highlight the close …
is proposed to replace non-alcoholic fatty liver disease (NAFLD) to highlight the close …