Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause
of cancer-related mortality rates worldwide. Although modern research was able to shed …

The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

The histologic examination of endoscopic biopsies or resection specimens remains a key
step in the work-up of affected inflammatory bowel disease (IBD) patients and can be used …

Research conducted during the past 30 years has increased our understanding of the
mechanisms involved in colorectal cancer initiation and development. The findings have …

Abstract Background/Aims: Hypoxia occurs in many pathological conditions, including
inflammation and cancer. Within this context, hypoxia was shown to inhibit but also to …

Background The interaction of coagulation factors has been shown to go beyond their
traditional roles in hemostasis and to affect the development of inflammatory diseases. Key …

OBJECTIVES: Diabetes mellitus (DM) has been associated with an increased risk of
colorectal cancer (CRC). The American College of Gastroenterology Guidelines for …

Inflammatory bowel disease (IBD), as do most chronic inflammatory disorders, displays
unique features and confers different risk factors in male and female patients. Importantly …

Patients with long-standing ulcerative colitis and Crohn's disease have an increased risk of
developing colorectal cancer and patients with small intestinal Crohn's disease are at …

The chemokine receptor CXCR2 is a key mediator of neutrophil migration that also plays a
role in tumor development. However, CXCR2 influences tumors through multiple …