Flavonoids for treatment of Alzheimer's disease: An up to date review

JK Kim, SU Park - EXCLI journal, 2021 - excli.de
Flavonoids, an omnipresent class of polyphenolic compounds, are commonly present in
fruits, vegetables, and plant-derived beverages (Panche et al., 2016). To date, more than …

Synthesis and biological evaluation of chromanone-based derivatives as potential anti-neuroinflammatory agents

G Li, X Feng, W Wang, J Li, Y Shi, L Wang, C Hu - Bioorganic Chemistry, 2023 - Elsevier
As a privileged scaffold, chromanone has been extensively introduced in the design of drug
leads with diverse pharmacological features, particularly in the area of inflammatory …

[HTML][HTML] Plinia trunciflora Extract Administration Prevents HI-Induced Oxidative Stress, Inflammatory Response, Behavioral Impairments, and Tissue Damage in Rats

AVS Carvalho, RT Ribeiro, LE Durán-Carabali… - Nutrients, 2022 - mdpi.com
The disruption of redox homeostasis and neuroinflammation are key mechanisms in the
pathogenesis of brain hypoxia–ischemia (HI); medicinal plants have been studied as a …

[HTML][HTML] Progress of plant polyphenol extracts in treating depression by anti-neuroinflammatory mechanism: A review

Y Guo, Y Yang - Medicine, 2024 - journals.lww.com
There is a growing body of evidence supporting the involvement of central nervous system
inflammation in the pathophysiology of depression. Polyphenols are a diverse group of …

Alzheimer hastalığında antosiyaninlerin önemi

Y GÜÇER, Z Göktaş - Yüksek İhtisas Üniversitesi Sağlık Bilimleri …, 2023 - dergipark.org.tr
Giriş: Yirmi birinci yüzyılın en önemli sağlık sorunlarından biri haline gelen Alzheimer
demansında ana patalojik belirteçler amiloid plaklar ve nörofibriler yumaklardır. Beyinde …

Nuclear Factor Kappa B: A Nobel Therapeutic Target of Flavonoids Against Parkinson's Disease

NK Singh, A Singh - Combinatorial Chemistry & High …, 2024 - ingentaconnect.com
Parkinson's disease (PD), the most common brain-related neurodegenerative disorder, is
comprised of several pathophysiological mechanisms, such as mitochondrial dysfunction …

[HTML][HTML] Low cellular pyridoxal 5ʹ-phosphate levels decrease neurotransmitter and glutathione concentrations and increase susceptibility to hydrogen peroxide …

N Itoh, S Matsumura, T Iwaki, S Takenaka… - Clinical Nutrition Open …, 2024 - Elsevier
Summary Objectives Pyridoxal 5ʹ-phosphate (PLP) is an active and major form of vitamin B
6 (VB 6) in the body. PLP is essential as a cofactor for many enzymes involved in amino acid …

Антоцианы для профилактики и лечения нейродегенеративных заболеваний

АБ Катасонов - Журнал неврологии и психиатрии им. СС Корсакова, 2022 - elibrary.ru
Антоцианы-это водорастворимые пигменты полифенольной природы, широко
представленные в овощах и фруктах. Эти соединения обладают обширной …

[HTML][HTML] Potential therapeutic targets and molecular details of anthocyan-treated inflammatory bowel disease: a systematic bioinformatics analysis of network …

Y Lin, L Luo, H Lin, X Li, R Huang - RSC advances, 2021 - pubs.rsc.org
Anthocyans, containing anthocyanins and anthocyanidins, play a crucial role in preventing
and treating inflammatory bowel disease (IBD). Most anthocyanins and their basic elements …

用于帕金森研究的脂多糖小鼠模型: 批判性评估

I Deng, L Bobrovskaya - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Parkinson's disease, the most common movement disorder, has a strong neuroinflammatory
aspect. This is evident by increased pro-inflammatory cytokines in the serum, and the …