Development of liver inflammatory injury in biliary atresia: from basic to clinical research

S Chusilp, F Balsamo, B Li, P Vejchapipat… - Pediatric Surgery …, 2023 - Springer
Biliary atresia (BA) is a severe cholangiopathy in infants. It is characterized by inflammatory
fibro-obliteration of the intra-and extrahepatic bile ducts. Although the restoration of bile flow …

Early and peri-operative prognostic indicators in infants undergoing hepatic portoenterostomy for biliary atresia: a review

RN Lopez, CY Ooi, U Krishnan - Current gastroenterology reports, 2017 - Springer
Abstract Purpose of Review Biliary atresia is the most common indication for liver
transplantation among children. In recent years, prospective, multi-centre collaboration has …

Predicting native liver injury and survival in biliary atresia

M Hukkinen, M Pihlajoki, MP Pakarinen - Seminars in Pediatric Surgery, 2020 - Elsevier
Several patient and treatment related factors significantly modify outcomes of biliary atresia.
The extremely variable prognosis mandates intensive postoperative monitoring following …

Insight into bile duct reaction to obstruction from a three-dimensional perspective using ex vivo phase-contrast CT

WJ Lv, XY Zhao, DD Hu, XH Xin, LL Qin, CH Hu - Radiology, 2021 - pubs.rsna.org
Background Biliary obstruction leads to an increase in biliary pressure within the biliary
system, which induces the morphologic adaptation of the biliary tree. Purpose To observe …

APRi predicts native liver survival by reflecting portal fibrogenesis and hepatic neovascularization at the time of portoenterostomy in biliary atresia

JS Suominen, H Lampela, P Heikkilä, J Lohi… - Journal of Pediatric …, 2015 - Elsevier
Background Aspartate aminotransferase-to-platelet ratio index (APRi) may be useful
noninvasive prognostic tool in biliary atresia (BA). We studied whether APRi predicts native …

Molecular signature of active fibrogenesis prevails in biliary atresia after successful portoenterostomy

A Kerola, H Lampela, J Lohi, P Heikkilä, A Mutanen… - Surgery, 2017 - Elsevier
Background In biliary atresia mechanisms of progressive liver injury leading to need of liver
transplantation after successful portoenterostomy remain unknown. A better understanding …

[HTML][HTML] Biliary atresia recent insight

RM Ghazy, NM Adawy, MA Khedr… - Egyptian Pediatric …, 2018 - Elsevier
Biliary atresia (BA) is a rare disease characterized by ascending obstruction of bile ducts
that exclusively affects newborn infants. The etiology of the disease is not known. BA is …

Fractionated bilirubin among 252 892 Utah newborns with and without biliary atresia: A 15-year Historical Birth Cohort Study

ZJ Kastenberg, MR Deneau, EA O'Brien, K Huynh… - The Journal of …, 2023 - Elsevier
Objectives To determine whether neonatal conjugated or direct bilirubin levels were
elevated in infants with biliary atresia (BA) and to estimate the number of newborns who …

[HTML][HTML] Prognostic molecular markers in pediatric liver disease–Are there any?

J Nielsen, VB Christensen, L Borgwardt… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Pediatric liver disease (PLD) is a major cause of severe morbidity and prolonged
hospitalizations in children. Stratifying patients in terms of prognosis remains challenging …

[HTML][HTML] Expression of 6 biomarkers in liver grafts after pediatric liver transplantation: correlations with histology, biochemistry, and outcome

SH Voutilainen, SK Kosola, J Lohi, A Mutka… - Annals of …, 2020 - ncbi.nlm.nih.gov
Expression of 6 Biomarkers in Liver Grafts After Pediatric Liver Transplantation: Correlations
with Histology, Biochemistry, and Outcome - PMC Back to Top Skip to main content NIH NLM …