Direct oral anticoagulant use: a practical guide to common clinical challenges

A Chen, E Stecker, B A. Warden - Journal of the American Heart …, 2020 - Am Heart Assoc
Direct oral anticoagulants (DOAC s) have quickly become attractive alternatives to the long‐
standing standard of care in anticoagulation, vitamin K antagonist. DOAC s are indicated for …

Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments

JL Mega, T Simon - The Lancet, 2015 - thelancet.com
Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, prevent and
treat many cardiovascular disorders and, as such, are some of the most commonly …

Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation …

JAC Sterne, PN Bodalia, PA Bryden… - Health Technology …, 2017 - discovery.ucl.ac.uk
BACKGROUND: Warfarin is effective for stroke prevention in atrial fibrillation (AF), but
anticoagulation is underused in clinical care. The risk of venous thromboembolic disease …

Management of Atrial Fibrillation in Patients 75 Years and Older: JACC State-of-the-Art Review

AS Volgman, G Nair, R Lyubarova, FM Merchant… - Journal of the American …, 2022 - jacc.org
The prevalence of atrial fibrillation (AF) is increasing as the population ages. AF treatment-
related complications also increase markedly in older adults (defined as≥ 75 years of age …

Cost-effectiveness of screening for atrial fibrillation in primary care with a handheld, single-lead electrocardiogram device in the Netherlands

MS Jacobs, F Kaasenbrood, MJ Postma… - Ep …, 2018 - academic.oup.com
Aims Atrial fibrillation (AF) is the most common arrhythmia and prevalence increases with
age. Patients with AF have a high risk of stroke, and screening for AF is recommended in all …

New oral anticoagulants in patients with nonvalvular atrial fibrillation: a review of pharmacokinetics, safety, efficacy, quality of life, and cost effectiveness

H Mani, E Lindhoff-Last - Drug design, development and therapy, 2014 - Taylor & Francis
Atrial fibrillation (AF) continues to be a leading cause of cerebrovascular morbidity and
mortality resulting from cardioembolic stroke. Oral anticoagulation therapy has been shown …

Evaluation of bleeding in patients receiving direct oral anticoagulants

EL Hellenbart, KD Faulkenberg… - Vascular health and risk …, 2017 - Taylor & Francis
Direct oral anticoagulants (DOACs) are recognized by evidence-based treatment guidelines
as the first-line option for the treatment of venous thromboembolism and prevention of stroke …

[HTML][HTML] Direct oral anticoagulants: analysis of worldwide use and popularity using Google Trends

G Lippi, C Mattiuzzi, G Cervellin… - Annals of translational …, 2017 - ncbi.nlm.nih.gov
Background Four direct oral anticoagulants (DOACs) have been approved for clinical use by
many medicines regulatory agencies around the world. Due to increasing use of these drugs …

Trends in hospitalization for atrial fibrillation: epidemiology, cost, and implications for the future

A Sheikh, NJ Patel, N Nalluri, K Agnihotri… - Progress in …, 2015 - Elsevier
Atrial fibrillation (AF) is the most prevalent arrhythmia worldwide and the most common
arrhythmia leading to hospitalization. Due to a substantial increase in incidence and …

Rivaroxaban vs warfarin sodium in the ultra-early period after atrial fibrillation–related mild ischemic stroke: a randomized clinical trial

KS Hong, SU Kwon, SH Lee, JS Lee, YJ Kim… - JAMA …, 2017 - jamanetwork.com
Importance In atrial fibrillation (AF)–related acute ischemic stroke, the optimal oral
anticoagulation strategy remains unclear. Objective To test whether rivaroxaban or warfarin …