Exploring the multifaceted biologically relevant roles of circRNAs: from regulation, translation to biomarkers

P Hoque, B Romero, RE Akins, M Batish - Cells, 2023 - mdpi.com
CircRNAs are a category of regulatory RNAs that have garnered significant attention in the
field of regulatory RNA research due to their structural stability and tissue-specific …

[HTML][HTML] Role of long noncoding RNAs in pathological cardiac remodeling after myocardial infarction: an emerging insight into molecular mechanisms and therapeutic …

A Yaghoobi, M Rezaee, AH Behnoush, A Khalaji… - Biomedicine & …, 2024 - Elsevier
Myocardial infarction (MI) is the leading cause of heart failure (HF), accounting for high
mortality and morbidity worldwide. As a consequence of ischemia/reperfusion injury during …

Propofol synergizes with circAPBB2 to protect against hypoxia/reoxygenation‐induced oxidative stress, inflammation, and apoptosis of human cardiomyocytes

C Jin, S Yuan, L Piao, M Ren… - Immunity, Inflammation and …, 2023 - Wiley Online Library
Background Myocardial injury is the main manifestation of cardiovascular diseases, and
previous studies have shown that propofol (PPF) regulates myocardial injury. However, the …

Novel insights into the molecular mechanisms governing embryonic epicardium formation

R Carmona, C López-Sánchez… - Journal of …, 2023 - mdpi.com
The embryonic epicardium originates from the proepicardium, an extracardiac primordium
constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is …

[HTML][HTML] Research trends and hotspots of circular RNA in cardiovascular disease: A bibliometric analysis

Z Xu, C Guan, Z Cheng, H Zhou, W Qin, J Feng… - Non-coding RNA …, 2024 - Elsevier
From a global perspective, cardiovascular diseases (CVDs), the leading factor accounting
for population mortality, and circRNAs, RNA molecules with stable closed-loop structures …

Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities

G Bononi, V Citi, A Martelli, G Poli… - RSC Medicinal …, 2024 - pubs.rsc.org
Sirtuin 1 (SIRT1) is an enzyme that relies on NAD+ cofactor and functions as a deacetylase.
It has been associated with various biological and pathological processes, including cancer …