Colorectal cancer development and advances in screening

K Simon - Clinical interventions in aging, 2016 - Taylor & Francis
Most colon tumors develop via a multistep process involving a series of histological,
morphological, and genetic changes that accumulate over time. This has allowed for …

[HTML][HTML] Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase

Q Li, W Hu, WX Liu, LY Zhao, D Huang, XD Liu… - Gastroenterology, 2021 - Elsevier
Background & Aims Streptococcus thermophilus was identified to be depleted in patients
with colorectal cancer (CRC) by shotgun metagenomic sequencing of 526 multicohort fecal …

Diagnostic accuracy of CT for local staging of colon cancer: a systematic review and meta-analysis

E Nerad, MJ Lahaye, M Maas… - American Journal of …, 2016 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this article is to determine the accuracy of CT in the detection of
tumor invasion beyond the bowel wall and nodal involvement of colon carcinomas. A …

[HTML][HTML] TGF-β signaling in metastatic colorectal cancer (mCRC): from underlying mechanism to potential applications in clinical development

X Li, Y Wu, T Tian - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …

Trends in colorectal cancer mortality in Europe: retrospective analysis of the WHO mortality database

DA Ouakrim, C Pizot, M Boniol, M Malvezzi, M Boniol… - Bmj, 2015 - bmj.com
Objective To examine changes in colorectal cancer mortality in 34 European countries
between 1970 and 2011. Design Retrospective trend analysis. Data source World Health …

Screening of colorectal cancer: present and future

M Maida, FS Macaluso, G Ianiro… - Expert review of …, 2017 - Taylor & Francis
Introduction: Colorectal cancer (CRC) is the third most common cancer in males and second
in females, and the fourth most common cause of cancer death worldwide. Currently, about …

Role of adenomatous polyposis coli (APC) gene mutations in the pathogenesis of colorectal cancer; current status and perspectives

AS Aghabozorgi, A Bahreyni, A Soleimani, A Bahrami… - Biochimie, 2019 - Elsevier
Colorectal cancer (CRC) is one of the most common forms of solid tumors in the world with
high rates of mortality and morbidity. Most cases of CRCs are initiated by inactivating …

The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment

G Dalmasso, A Cougnoux, J Delmas… - Gut …, 2014 - Taylor & Francis
The gut microbiota is suspected to promote colorectal cancer (CRC). Escherichia coli are
more frequently found in CCR biopsies than in healthy mucosa; furthermore, the majority of …

Mediterranean diet and colorectal cancer: A systematic review

A Farinetti, V Zurlo, A Manenti, F Coppi, AV Mattioli - Nutrition, 2017 - Elsevier
Colorectal cancer is the third most common cancer worldwide, especially in developed
countries where an estimated 60% of all cases occur. There is evidence of a higher risk for …