Importance Depression is common and associated with substantial burden. Suicide rates
have increased over the past decade, and both suicide attempts and deaths have …

Chronic pain is one of the main leading causes of disability in the world at present. A variety
in the symptomatology, intensity and duration of this phenomenon has led to an ever …

Suicidal behavior is more prevalent in bipolar disorders than in other psychiatric illnesses. In
the last thirty years evidence has emerged to indicate that long-term treatment of bipolar …

There is concern regarding the impact of selective serotonin reuptake inhibitors (SSRIs) on
suicidal behaviour. Using the target trial framework, we investigated the effect on suicidal …

Objective: Suicide is a global health concern, and innovative interventions that target
suicidality are needed. While psychedelic therapy shows promise for a range of mental …

The landscape of mental health care and service delivery is changing, as is our
understanding of the underlying causes for mental distress. It is now apparent that biogenic …

Objectives To investigate if observational studies showing favorable results for
antidepressants on suicidal behavior (reduced risk) are preferably and more easily …

Medicine is supposed to make progress, to go forward in scientific terms so that each
successive generation knows more and does better than previous generations. This hasn't …

Antidepressant medication (ADM)-only, psychotherapy-only, and their combination are the
first-line treatment options for major depressive disorder (MDD). Previous meta-analyses of …

Objective The mechanism of Wendan Decoction (WDD) against Generalized Anxiety
Disorder (GAD) was predicted by network pharmacology and validated by in vivo and in vitro …