Learning Objective: After participating in this activity, learners should be better able to:
Evaluate the rationale for and current evidence supporting medication-assisted treatment of …

Retention in medication-assisted treatment among opiate-dependent patients is associated
with better outcomes. This systematic review (55 articles, 2010–2014) found wide variability …

Objectives. We estimated national and state trends in opioid agonist medication-assisted
treatment (OA-MAT) need and capacity to identify gaps and inform policy decisions …

Fentanyl is a powerful opioid anesthetic and analgesic, the use of which has caused an
increasing public health threat in the United States and elsewhere. Fentanyl was initially …

The prevalence of opioid use and misuse has provoked a staggering number of deaths over
the past two and a half decades. Much attention has focused on individual risks according to …

The toll of untreated opioid use disorder is tremendous. In 2015, 33,091 Americans died
from a drug overdose involving an opioid. In just one year, the death rate from heroin …

Social isolation during opioid withdrawal is a major contributor to the current opioid
addiction crisis. We find that sociability deficits during protracted opioid withdrawal in mice …

Introduction: The opioid epidemic has become an immense problem in North America, and
despite decades of research on the most effective means to treat opioid use disorder (OUD) …

Background The past two decades have witnessed an epidemic of opioid use disorder
(OUD) in the USA, resulting in catastrophic loss of life secondary to opioid overdoses …

Buprenorphine treatment for opioid use disorder is safe and effective, but only a fraction of
Americans who need treatment receive it. One reason for this is that many buprenorphine …