Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

The appearance of new dominant variants of concern (VOC) of severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) threatens the global response to the …

Since the spread of the deadly virus SARS-CoV-2 in late 2019, researchers have restlessly
sought to unravel how the virus enters the host cells. Some proteins on each side of the …

Successful severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
requires proteolytic cleavage of the viral spike protein. While the role of the host …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic. Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for SARS-CoV-2 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remained genetically
stable during the first 3 months of the pandemic, before acquiring a D614G spike mutation …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike glycoprotein (S)
binds to angiotensin-converting enzyme 2 (ACE2) to mediate membrane fusion via two …

Abstract The SARS-CoV-2 Omicron variant reportedly displays decreased usage of the cell
surface entry pathway mediated by the host transmembrane protease, serine 2 (TMPRSS2) …

The emergence of SARS-CoV-2 variants represents a major threat to public health and
requires identification of novel therapeutic agents to address the unmet medical needs …

Coronaviruses, including SARS-CoV-2, SARS-CoV, MERS-CoV and influenza A virus,
require the host proteases to mediate viral entry into cells. Rather than targeting the …