Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …

The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Hydrogels provide a promising platform for cartilage repair and regeneration. Although
hydrogels have shown some efficacy, they still have shortcomings including poor …

Intrinsically present bioactive cues allow naturally derived materials to mimic important
characteristics of cartilage while also facilitating cellular recruitment, infiltration, and …

Despite critical advances in regenerative medicine, the generation of definitive, reliable
treatments for musculoskeletal diseases remains challenging. Gene therapy based on the …

Cartilage has limited self-repair ability and often degenerates after injury if left untreated.
This thesis presents the development of a novel photo-cross-linkable GelMA-glycol chitosan …