Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes

HS Kwon, SH Koh - Translational neurodegeneration, 2020 - Springer
Neuroinflammation is associated with neurodegenerative diseases, such as Alzheimer's
disease, Parkinson's disease, and amyotrophic lateral sclerosis. Microglia and astrocytes …

Gut–brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain …

K Suganya, BS Koo - International journal of molecular sciences, 2020 - mdpi.com
The gut microbiome acts as an integral part of the gastrointestinal tract (GIT) that has the
largest and vulnerable surface with desirable features to observe foods, nutrients, and …

[HTML][HTML] The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease

B Brakedal, C Dölle, F Riemer, Y Ma, GS Nido… - Cell metabolism, 2022 - cell.com
We conducted a double-blinded phase I clinical trial to establish whether nicotinamide
adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside …

Natural products from cyanobacteria: Focus on beneficial activities

J Demay, C Bernard, A Reinhardt, B Marie - Marine drugs, 2019 - mdpi.com
Cyanobacteria are photosynthetic microorganisms that colonize diverse environments
worldwide, ranging from ocean to freshwaters, soils, and extreme environments. Their …

The gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis?

MC Houser, MG Tansey - NPJ Parkinson's disease, 2017 - nature.com
The state of the intestinal environment can have profound effects on the activity of the central
nervous system through the physiological contributions of the microbiota, regulation of …

[HTML][HTML] Neuroinflammation induces neurodegeneration

D Kempuraj, R Thangavel, PA Natteru… - Journal of neurology …, 2016 - ncbi.nlm.nih.gov
Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
and Multiple Sclerosis (MS) are characterized by neuronal degeneration and neuronal …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021 - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

Gut dysbiosis, defective autophagy and altered immune responses in neurodegenerative diseases: Tales of a vicious cycle

SB Chidambaram, MM Essa, AG Rathipriya… - Pharmacology & …, 2022 - Elsevier
The human microbiota comprises trillions of symbiotic microorganisms and is involved in
regulating gastrointestinal (GI), immune, nervous system and metabolic homeostasis …

Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

ME Haque, M Akther, M Jakaria, IS Kim… - Movement …, 2020 - Wiley Online Library
Excessive activation of microglia and subsequent release of proinflammatory cytokines play
a crucial role in neuroinflammation and neurodegeneration in Parkinson's disease (PD) …

The role of neuroimmune signaling in alcoholism

FT Crews, CJ Lawrimore, TJ Walter, LG Coleman Jr - Neuropharmacology, 2017 - Elsevier
Alcohol consumption and stress increase brain levels of known innate immune signaling
molecules. Microglia, the innate immune cells of the brain, and neurons respond to alcohol …