The drug-receptor binding kinetics are defined by the rate at which a given drug associates
with and dissociates from its binding site on its macromolecular receptor. The lead …

Sir, Medical science is witnessing a progressive revolution and evolution throughout the
globe with continual improvement in diagnostics and therapeutic interventions. The literary …

Factor X is one of the main enzymes in blood coagulation cascade. It is present at the middle
point of intrinsic and extrinsic pathways and become activated once an injury occur. Its basic …

The article provides a brief description of drugs in the class of direct oral anticoagulants. The
mechanisms of the therapeutic effect and the ways of excretion of drugs-inhibitors of blood …

One of the main causes involved in acquired hemorrhagic disturbs are the side effects of
antithrombotic drugs that can lead to bleeding complications due to overdosage or …

В статье представлена краткая характеристика препаратов класса прямых оральных
антикоагулянтов. Рассматриваются механизмы терапевтического воздействия и пути …

Obwohl der Einsatz der Faktor Xa-Inhibitoren keines routinemäßigen Monitorings bedarf,
gibt es Situationen im klinischen Alltag, in denen eine Einschätzung ihrer Wirkung …

For decades, vitamin K antagonist warfarin has been used for thromboprophylaxis or stroke
prevention in atrial fibrillation. Recently, direct thrombin inhibitor-dabigatran and factor Xa …

Sir, Medical science is witnessing a progressive revolution and evolution throughout the
globe with continual improvement in diagnostics and therapeutic interventions. The literary …