Lipidomic approaches to dissect dysregulated lipid metabolism in kidney disease
J Baek, C He, F Afshinnia, G Michailidis… - Nature Reviews …, 2022 - nature.com
Dyslipidaemia is a hallmark of chronic kidney disease (CKD). The severity of dyslipidaemia
not only correlates with CKD stage but is also associated with CKD-associated …
not only correlates with CKD stage but is also associated with CKD-associated …
[HTML][HTML] Exploring the lipidome: current lipid extraction techniques for mass spectrometry analysis
In recent years, high-throughput lipid profiling has contributed to understand the biological,
physiological and pathological roles of lipids in living organisms. Across all kingdoms of life …
physiological and pathological roles of lipids in living organisms. Across all kingdoms of life …
[HTML][HTML] Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation
RG Snodgrass, Y Benatzy, T Schmid… - Cell Death & …, 2021 - nature.com
Macrophages acquire anti-inflammatory and proresolving functions to facilitate resolution of
inflammation and promote tissue repair. While alternatively activated macrophages (AAMs) …
inflammation and promote tissue repair. While alternatively activated macrophages (AAMs) …
[图书][B] Liquid chromatography: applications
Liquid Chromatography: Applications, Second Edition, is a single source of authoritative
information on all aspects of the practice of modern liquid chromatography. It gives those …
information on all aspects of the practice of modern liquid chromatography. It gives those …
[HTML][HTML] Development of a quantitative proteomics approach for cyclooxygenases and lipoxygenases in parallel to quantitative oxylipin analysis allowing the …
NM Hartung, M Mainka, R Pfaff, M Kuhn… - Analytical and …, 2023 - Springer
Oxylipins derived from the cyclooxygenase (COX) and lipoxygenase (LOX) pathways of the
arachidonic acid (ARA) cascade are essential for the regulation of the inflammatory …
arachidonic acid (ARA) cascade are essential for the regulation of the inflammatory …
[HTML][HTML] Development of an optimized LC-MS method for the detection of specialized pro-resolving mediators in biological samples
L Kutzner, KM Rund, AI Ostermann… - Frontiers in …, 2019 - frontiersin.org
The cardioprotective and anti-inflammatory effects of long chain omega-3 polyunsaturated
fatty acids (n3 PUFA) are believed to be partly mediated by their oxygenated metabolites …
fatty acids (n3 PUFA) are believed to be partly mediated by their oxygenated metabolites …
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10
FC Richter, M Friedrich, N Kampschulte, K Piletic… - The EMBO …, 2023 - embopress.org
Lipids play a major role in inflammatory diseases by altering inflammatory cell functions,
either through their function as energy substrates or as lipid mediators such as oxylipins …
either through their function as energy substrates or as lipid mediators such as oxylipins …
MS-based targeted metabolomics of eicosanoids and other oxylipins: Analytical and inter-individual variabilities
Oxylipins, including the well-known eicosanoids, are potent lipid mediators involved in
numerous physiological and pathological processes. Therefore, their quantitative profiling …
numerous physiological and pathological processes. Therefore, their quantitative profiling …
[HTML][HTML] Plasma oxylipins respond in a linear dose-response manner with increased intake of EPA and DHA: results from a randomized controlled trial in healthy …
AI Ostermann, AL West, K Schoenfeld… - The American journal of …, 2019 - Elsevier
Background The health effects of long-chain omega-3 polyunsaturated fatty acids (n–3
PUFAs) are partly mediated by their oxidized metabolites, ie, eicosanoids and other …
PUFAs) are partly mediated by their oxidized metabolites, ie, eicosanoids and other …
Moving forward with isoprostanes, neuroprostanes and phytoprostanes: where are we now?
OS Ahmed, JM Galano, T Pavlickova… - Essays in …, 2020 - portlandpress.com
Polyunsaturated fatty acids (PUFAs) are essential components in eukaryotic cell membrane.
They take part in the regulation of cell signalling pathways and act as precursors in …
They take part in the regulation of cell signalling pathways and act as precursors in …