Background In case of bleeding patients and in acute care, the assessment of residual direct
oral anticoagulant (DOAC) activity is essential for evaluating the potential impact on …

The monitoring of coagulation by viscoelastometric methods—thromboelastography and
rotational thromboelastometry—may detect the contributions of cellular and plasma …

In urgent clinical situations, such as trauma, urgent surgery or before thrombolysis, rapid
quantification of direct oral anticoagulant plasma drug levels is warranted. Using the …

From preoperative medications to intraoperative needs to postoperative
thromboprophylaxis, anticoagulants are encountered throughout the perioperative period …

Background The aim of this study was to analyze the changing role of thrombelastography
(TEG) by detecting the indexes of TEG in patients with acute cerebral hemorrhage and …

Introduction Timely measurement of direct oral anticoagulants (DOACs) is challenging,
though clinically important. We tested the hypotheses, that thromboelastometry is able to …

Introduction Thromboelastography (TEG) provides a global assessment of hemostasis and
may have value for patients with cirrhosis who have multiple hemostatic defects. We sought …

Essentials• A rapid test to detect thrombin inhibition by dabigatran would be valuable in
acute situations.• A thrombin‐based trigger was applied in whole blood using rotation …

Background SAR107375E is a direct dual inhibitor of both Factor Xa and Factor IIa and has
shown potent anticoagulation activity in vitro and animals. This study evaluated the safety …

Purpose Dabigatran concentrations monitoring are gaining importance of special situations,
but limited data are available for the expected peak and trough levels. The hemoclot …