Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows
Therapeutic drug monitoring is essential for dosing pharmaceuticals with narrow therapeutic
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …
Cystic fibrosis year in review 2020: Section 2 pulmonary disease, infections, and inflammation
NJ Antos, AP Savant - Pediatric Pulmonology, 2022 - Wiley Online Library
The outlook for those with cystic fibrosis (CF) has never been brighter with ever increasing
life expectancy and the approval of the highly effective CFTR modulators, such as …
life expectancy and the approval of the highly effective CFTR modulators, such as …
Pharmacokinetic modelling to predict risk of ototoxicity with intravenous tobramycin treatment in cystic fibrosis
M Dong, AV Rodriguez, CA Blankenship… - Journal of …, 2021 - academic.oup.com
Introduction Further optimization of therapeutic drug monitoring (TDM) for aminoglycosides
(AGs) is urgently needed, especially in special populations such as those with cystic fibrosis …
(AGs) is urgently needed, especially in special populations such as those with cystic fibrosis …
Personalized tobramycin dosing in children with cystic fibrosis: a comparative clinical evaluation of log-linear and Bayesian methods
S Imani, DA Fitzgerald, PD Robinson… - Journal of …, 2022 - academic.oup.com
Background Children with cystic fibrosis (CF) pulmonary exacerbations receive IV
tobramycin therapy, with dosing guided by either log-linear regression (LLR) or Bayesian …
tobramycin therapy, with dosing guided by either log-linear regression (LLR) or Bayesian …
Population pharmacokinetic modeling and dosing simulations of tobramycin in pediatric patients with cystic fibrosis
A Praet, L Bourguignon, F Vetele, V Breant… - Antimicrobial agents …, 2021 - Am Soc Microbiol
Initial dosing and dose adjustment of intravenous tobramycin in children with cystic fibrosis
(CF) is challenging. The objectives of this study were to develop nonparametric population …
(CF) is challenging. The objectives of this study were to develop nonparametric population …
A pharmacokinetic analysis of tobramycin in patients less than five years of age with cystic fibrosis: Assessment of target attainment with extended-interval dosing …
KJ Downes, A Grim, L Shanley… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Extended interval dosing of tobramycin is recommended for treatment of pulmonary
exacerbations in adults and older children with cystic fibrosis (CF), but data are limited in …
exacerbations in adults and older children with cystic fibrosis (CF), but data are limited in …
Target attainment of extended-interval dosing of tobramycin in patients less than five years of age with cystic fibrosis: A pharmacokinetic analysis
KJ Downes, A Grim, L Shanley, RC Rubenstein… - medRxiv, 2022 - medrxiv.org
Background Extended interval dosing (EID) of tobramycin is recommended for treatment of
pulmonary exacerbations in adults and older children with cystic fibrosis (CF), but data are …
pulmonary exacerbations in adults and older children with cystic fibrosis (CF), but data are …
Personalised Antimicrobial Dosing in Paediatric Cystic Fibrosis
S Imani - 2022 - researchonline.nd.edu.au
Children with cystic fibrosis (CF) are predisposed to recurrent pulmonary exacerbations
throughout their lifetime. This is characterised by an acute worsening of respiratory …
throughout their lifetime. This is characterised by an acute worsening of respiratory …
[图书][B] Ubiquitous non-and minimally-invasive biosensing technologies for personalized and precision medicine
S Lin - 2022 - search.proquest.com
Recent advances in miniaturized electronics, microfluidics, and electrochemical sensing
platforms have paved the path for the realization of wearable and mobile biosensing …
platforms have paved the path for the realization of wearable and mobile biosensing …