Age-related macular degeneration

M Fleckenstein, TDL Keenan, RH Guymer… - Nature reviews Disease …, 2021 - nature.com
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the
industrialized world. AMD is characterized by accumulation of extracellular deposits, namely …

[HTML][HTML] Progression from early/intermediate to advanced forms of age-related macular degeneration in a large UK cohort: rates and risk factors

U Chakravarthy, CC Bailey, PH Scanlon… - Ophthalmology …, 2020 - Elsevier
Purpose To estimate rates and risk factors for progression to geographic atrophy (GA) or
choroidal neovascularization (CNV) among eyes diagnosed with early or intermediate age …

[HTML][HTML] Global burden of dry age-related macular degeneration: a targeted literature review

NM Schultz, S Bhardwaj, C Barclay, L Gaspar… - Clinical …, 2021 - Elsevier
Purpose Age-related macular degeneration (AMD) is a leading cause of blindness,
particularly in higher-income countries. Although dry AMD accounts for 85% to 90% of AMD …

Age-related macular degeneration: pathophysiology, management, and future perspectives

R Flores, Â Carneiro, M Vieira, S Tenreiro… - Ophthalmologica, 2021 - karger.com
Among older adults, age-related macular degeneration (AMD) is a prevalent disabling
condition that begins as subtle visual disturbances and can progress to permanent loss of …

Age-related macular degeneration: A two-level model hypothesis

MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …

Mediterranean diet and incidence of advanced age-related macular degeneration: the EYE-RISK Consortium

BMJ Merle, JM Colijn, A Cougnard-Grégoire… - Ophthalmology, 2019 - Elsevier
Purpose To investigate associations of adherence to the Mediterranean diet (MeDi) with
incidence of advanced age-related macular degeneration (AMD; the symptomatic form of …

Age-related macular degeneration: epidemiology and clinical aspects

TDL Keenan, CA Cukras, EY Chew - … : From Clinic to Genes and Back to …, 2021 - Springer
Age-related macular degeneration (AMD) is a degenerative disease of the human retina
affecting individuals over the age of 55 years. This heterogeneous condition arises from a …

Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration

Y Pan, Y Fu, PN Baird, RH Guymer, T Das… - Progress in Retinal and …, 2023 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of severe irreversible central
vision loss in individuals over 65 years old. Genome-wide association studies (GWASs) …

[HTML][HTML] Genetic risk, lifestyle, and age-related macular degeneration in Europe: the EYE-RISK Consortium

JM Colijn, M Meester-Smoor, T Verzijden, A de Breuk… - Ophthalmology, 2021 - Elsevier
Purpose Age-related macular degeneration (AMD) is a common multifactorial disease in the
elderly with a prominent genetic basis. Many risk variants have been identified, but the …

Undertreatment of neovascular age-related macular degeneration after 10 years of anti-vascular endothelial growth factor therapy in the real world: the need for a …

J Monés, RP Singh, F Bandello, E Souied, X Liu… - …, 2020 - karger.com
Purpose: To assess the gap between visual acuity (VA) outcomes with anti-vascular
endothelial growth factor (anti-VEGF) therapies in clinical trials and real-world practice, and …