[HTML][HTML] Neovascular progression and retinal dysfunction in the laser-induced choroidal neovascularization mouse model
The mouse model of laser-induced choroidal neovascularization (LI-CNV) has been widely
used to study neovascular age-related macular degeneration; however, it still lacks a …
used to study neovascular age-related macular degeneration; however, it still lacks a …
[HTML][HTML] Machine learning-based automated detection and quantification of geographic atrophy and hypertransmission defects using spectral domain optical …
The current study describes the development and assessment of innovative, machine
learning (ML)-based approaches for automated detection and pixel-accurate measurements …
learning (ML)-based approaches for automated detection and pixel-accurate measurements …
Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans
MM Mauschitz, T Verzijden, AK Schuster… - British Journal of …, 2023 - bjo.bmj.com
Background/aims To investigate the association of commonly used systemic medications
with prevalent age-related macular degeneration (AMD) in the general population. Methods …
with prevalent age-related macular degeneration (AMD) in the general population. Methods …
[HTML][HTML] DRD2 activation inhibits choroidal neovascularization in patients with Parkinson's disease and age-related macular degeneration
T Mathis, F Baudin, AS Mariet, S Augustin… - The Journal of clinical …, 2024 - jci.org
Neovascular age-related macular degeneration (nAMD) remains a major cause of visual
impairment and puts considerable burden on patients and health care systems. l-DOPA …
impairment and puts considerable burden on patients and health care systems. l-DOPA …
[HTML][HTML] Genotype-and phenotype-based subgroups in geographic atrophy secondary to age-related macular degeneration: the EYE-RISK Consortium
Purpose Geographic atrophy (GA) secondary to age-related macular degeneration is
considered a single entity. This study aimed to determine whether GA subgroups exist that …
considered a single entity. This study aimed to determine whether GA subgroups exist that …
[HTML][HTML] Monitoring for neovascular age-related macular degeneration (AMD) reactivation at home: the MONARCH study
E Ward, RA Wickens, A O'Connell, LA Culliford… - Eye, 2021 - nature.com
Aims This study aims to quantify the diagnostic test-accuracy of three visual function self-
monitoring tests for detection of active disease in patients with neovascular age-related …
monitoring tests for detection of active disease in patients with neovascular age-related …
[HTML][HTML] Clinical study protocol for a low-interventional study in intermediate age-related macular degeneration developing novel clinical endpoints for interventional …
Background There is an unmet need for treatment options in intermediate age-related
macular degeneration (iAMD). However, for any new interventions to be tested in clinical …
macular degeneration (iAMD). However, for any new interventions to be tested in clinical …
[HTML][HTML] Detecting vision loss in intermediate age-related macular degeneration: a comparison of visual function tests
SG Pondorfer, M Heinemann, MWM Wintergerst… - PLoS …, 2020 - journals.plos.org
The purpose of the study was to evaluate the diagnostic accuracy of visual function tests in
intermediate age-related macular degeneration (iAMD). A total of 62 subjects (38 patients …
intermediate age-related macular degeneration (iAMD). A total of 62 subjects (38 patients …
Clinical role of epigenetics and network analysis in eye diseases: a translational science review
M Lanza, G Benincasa, D Costa… - Journal of …, 2019 - Wiley Online Library
Network medicine is a molecular‐bioinformatic approach analyzing gene‐gene interactions
that can perturb the human interactome. This review focuses on epigenetic changes …
that can perturb the human interactome. This review focuses on epigenetic changes …
Association of genetic variants with response to anti–vascular endothelial growth factor therapy in age-related macular degeneration
Importance Visual acuity (VA) outcomes differ considerably among patients with
neovascular age-related macular degeneration (nAMD) treated with anti–vascular …
neovascular age-related macular degeneration (nAMD) treated with anti–vascular …