Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY Xie - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Micro/nanorobotic swarms: from fundamentals to functionalities

J Law, J Yu, W Tang, Z Gong, X Wang, Y Sun - ACS nano, 2023 - ACS Publications
Swarms, which stem from collective behaviors among individual elements, are commonly
seen in nature. Since two decades ago, scientists have been attempting to understand the …

Magnetic microswarm and fluoroscopy‐guided platform for biofilm eradication in biliary stents

M Sun, KF Chan, Z Zhang, L Wang, Q Wang… - Advanced …, 2022 - Wiley Online Library
Biofilm eradication from medical implants is of fundamental importance, and the treatment of
biofilm‐associated pathogen infections on inaccessible biliary stents remains challenging …

Biomaterials for in situ cell therapy

C Wang, S Wang, DD Kang, Y Dong - BMEMat, 2023 - Wiley Online Library
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …

Ultrasound-responsive catalytic microbubbles enhance biofilm elimination and immune activation to treat chronic lung infections

W Xiu, L Ren, H Xiao, Y Zhang, D Wang, K Yang… - Science …, 2023 - science.org
Efficient treatment of chronic lung infections caused by Pseudomonas aeruginosa biofilms is
a great challenge because of drug tolerance and immune evasion issues. Here, we develop …

Magnetic–acoustic sequentially actuated CAR T cell microrobots for precision navigation and in situ antitumor immunoactivation

X Tang, Y Yang, M Zheng, T Yin, G Huang… - Advanced …, 2023 - Wiley Online Library
Despite its clinical success, chimeric antigen receptor T (CAR T)‐cell immunotherapy
remains limited in solid tumors, owing to the harsh physical barriers and …

Swarming magnetic nanorobots bio-interfaced by heparinoid-polymer brushes for in vivo safe synergistic thrombolysis

M Yang, Y Zhang, F Mou, C Cao, L Yu, Z Li… - Science Advances, 2023 - science.org
Biocompatible swarming magnetic nanorobots that work in blood vessels for safe and
efficient targeted thrombolytic therapy in vivo are demonstrated. This is achieved by using …

Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

An overview of micronanoswarms for biomedical applications

H Chen, H Zhang, T Xu, J Yu - ACS nano, 2021 - ACS Publications
Micronanoswarms have attracted extensive attention worldwide due to their great promise in
biomedical applications. The collective behaviors among thousands, or even millions, of tiny …

From design to clinic: engineered nanobiomaterials for immune normalization therapy of cancer

M Saeed, F Chen, J Ye, Y Shi, T Lammers… - Advanced …, 2021 - Wiley Online Library
The tumor immune microenvironment (TIME) is comprised of a complex milieu that
contributes to stunting antitumor immune responses by restricting T cells to accumulate in …