Platelets, non-nucleated blood components first described over 130 years ago, are
recognized as the primary cell regulating hemostasis and thrombosis. The vascular …

The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Classically, platelets have been described as the cellular blood component that mediates
hemostasis and thrombosis. This important platelet function has received significant …

The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and
fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system …

While platelet function has traditionally been described in the context of maintaining
vascular integrity, recent evidence suggests that platelets can modulate inflammation in a …

Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

Metabolic diseases pose a tremendous health threat in both developed and developing
countries. The pathophysiology of metabolic diseases is complex but has been shown to be …

In the central nervous system (CNS), microglia are innate immune mononuclear phagocytes
(CNS MPs) that can phagocytose infectious particles, apoptotic cells, neurons, and …

Platelet–endothelial interactions have a critical role in microcirculatory function, which
maintains tissue homeostasis. The subtle equilibrium between platelets and the vessel wall …