[HTML][HTML] Research progress of anti-PD-1/PD-L1 immunotherapy related mechanisms and predictive biomarkers in NSCLC
F Bie, H Tian, N Sun, R Zang, M Zhang, P Song… - Frontiers in …, 2022 - frontiersin.org
Programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) is an important pair of
immune checkpoints (IC), which play an essential role in the immune escaping process of …
immune checkpoints (IC), which play an essential role in the immune escaping process of …
Contribution of genomics to the surgical management and study of oral cancer
Z Saidak, C Lailler, S Testelin, B Chauffert… - Annals of Surgical …, 2021 - Springer
Background Oral squamous cell carcinoma (OSCC) is the most frequent type of tumor
arising from the oral cavity. Surgery is the cornerstone of the treatment of these cancers …
arising from the oral cavity. Surgery is the cornerstone of the treatment of these cancers …
The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal …
Highlights Deregulation in MMR mechanism and miR-21, miR-155 and miR-451a are
caused by chronic exposure to N-Nitrosamines, NNK and NDEA, and nicotine. Reduced …
caused by chronic exposure to N-Nitrosamines, NNK and NDEA, and nicotine. Reduced …
[HTML][HTML] The Clinical Significance and Transcription Regulation of a DNA Damage Repair Gene, SMC4, in Low-Grade Glioma via Integrated Bioinformatic Analysis
Y Wang, Z Wu - Frontiers in Oncology, 2021 - frontiersin.org
Glioma is the most common type of malignant tumor in the central nervous system with an
unfavorable prognosis and limited treatment. In this study, we are devoted to addressing the …
unfavorable prognosis and limited treatment. In this study, we are devoted to addressing the …
MSIFinder: a python package for detecting MSI status using random forest classifier
T Zhou, L Chen, J Guo, M Zhang, Y Zhang, S Cao… - BMC …, 2021 - Springer
Background Microsatellite instability (MSI) is a common genomic alteration in colorectal
cancer, endometrial carcinoma, and other solid tumors. MSI is characterized by a high …
cancer, endometrial carcinoma, and other solid tumors. MSI is characterized by a high …
A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker
X Guo, M Huang, H Zhang, Q Chen, Y Hu… - Cancer Cell …, 2022 - Springer
Background The critical role of thioredoxin-interacting protein (TXNIP) in cellular sulfhydryl
redox homeostasis and inflammasome activation is already widely known, however, no pan …
redox homeostasis and inflammasome activation is already widely known, however, no pan …
[HTML][HTML] Promoter DNA methylation patterns in oral, laryngeal and oropharyngeal anatomical regions are associated with tumor differentiation, nodal involvement and …
B RiveRA‑PeñA, O Folawiyo, N Turaga… - Oncology …, 2024 - spandidos-publications.com
Differentially methylated regions (DMRs) can be used as head and neck squamous cell
carcinoma (HNSCC) diagnostic, prognostic and therapeutic targets in precision medicine …
carcinoma (HNSCC) diagnostic, prognostic and therapeutic targets in precision medicine …
Association of the lung immune prognostic index with immunotherapy outcomes in mismatch repair deficient tumors
Simple Summary Deficient Mismatch Repair (dMMR) is an oncogenic path accounting for
around 15% of cancers. It is considered as the first predictive marker of efficacy for immune …
around 15% of cancers. It is considered as the first predictive marker of efficacy for immune …
Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma
CAA Lee, S Wu, YT Chow, E Kofman, V Williams… - Journal of Investigative …, 2024 - Elsevier
Recessive dystrophic epidermolysis bullosa (RDEB) is a severely debilitating disorder
caused by mutations in COL7A1 and is characterized by extreme skin fragility, chronic …
caused by mutations in COL7A1 and is characterized by extreme skin fragility, chronic …
Translational insights and new therapeutic perspectives in head and neck tumors
Head and neck squamous cell carcinoma (HNSCC) is characterized by a high mortality rate
owing to very few available oncological treatments. For many years, a combination of …
owing to very few available oncological treatments. For many years, a combination of …