Importance of the pig as a human biomedical model

JK Lunney, A Van Goor, KE Walker… - Science translational …, 2021 - science.org
Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

Production of Pigs From Porcine Embryos Generated in vitro

PR Chen, K Uh, BK Redel, ED Reese… - Frontiers in Animal …, 2022 - frontiersin.org
Generating porcine embryos in vitro is a critical process for creating genetically modified
pigs as agricultural and biomedical models; however, these embryo technologies have been …

Conceptus Estrogen and prostaglandins provide the maternal recognition of pregnancy signal to prevent Luteolysis during early pregnancy in the pig

RM Sullivan, CG Lucas, M Sponchiado… - Biology of …, 2024 - academic.oup.com
Conceptus estrogens and prostaglandins have long been considered the primary signals for
maternal recognition of pregnancy (MRP) in the pig. However, loss-of-function studies …

Optimizing swine in vitro embryo production with growth factor and antioxidant supplementation during oocyte maturation

L Currin, WG Glanzner, K Gutierrez, MP de Macedo… - Theriogenology, 2022 - Elsevier
Porcine in vitro fertilization often results in low embryo development rates compared to other
livestock species, which is often associated with either a low fertilization rate or high …

Lack of airway submucosal glands impairs respiratory host defenses

LS Ostedgaard, MP Price, KM Whitworth… - Elife, 2020 - elifesciences.org
Submucosal glands (SMGs) are a prominent structure that lines human cartilaginous
airways. Although it has been assumed that SMGs contribute to respiratory defense, that …

25th ANNIVERSARY OF CLONING BY SOMATIC-CELL NUCLEAR TRANSFER: Current applications of SCNT in advanced breeding and genome editing in livestock

C Galli, G Lazzari - Reproduction, 2021 - rep.bioscientifica.com
SCNT (somatic cell nuclear transfer) has complemented the toolbox of ARTs offering yet
another technique to reproduce animals in an unprecedented way. Despite remarkable …

Alginate oligosaccharides increase boar semen quality by affecting gut microbiota and metabolites in blood and sperm

H Han, Y Zhou, B Xiong, R Zhong, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Alginate oligosaccharides (AOS), natural polymers from brown seaweeds (such as
Laminaria japonica, Undaria pinnatifida, and Sargassum fusiforme), have been reported to …

Mitochondrial metabolism assessment of lycaon-dog fetuses in interspecies somatic cell nuclear transfer

YB Son, YI Jeong, KC Hwang, YW Jeong, WS Hwang - Theriogenology, 2021 - Elsevier
Many studies have reported that interspecies somatic cell nuclear transfer (iSCNT) is
considered the prominent method in preserving endangered animals. However, the …

IVM advances for early antral follicle-enclosed oocytes coupling reproductive tissue engineering to inductive influences of human chorionic gonadotropin and ovarian …

A Peserico, C Di Berardino, G Capacchietti… - International Journal of …, 2023 - mdpi.com
In vitro maturation (IVM) is not a routine assisted reproductive technology (ART) for oocytes
collected from early antral (EA) follicles, a large source of potentially available gametes …

Meptyldinocap induces implantation failure by forcing cell cycle arrest, mitochondrial dysfunction, and endoplasmic reticulum stress in porcine trophectoderm and …

E Sung, W Park, J Park, FW Bazer, G Song… - Science of the Total …, 2024 - Elsevier
Meptyldinocap is a dinitrophenol fungicide used to control powdery mildew. Although other
dinitrophenol pesticides have been found to exhibit reproductive toxicity, studies of …