Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …

Nearly all infectious agents contain DNA or RNA genomes, making sequencing an attractive
approach for pathogen detection. The cost of high-throughput or next-generation …

Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing
the viruses carried by pangolins is a logical approach to evaluate the range of potential …

Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been
successfully tested in proof-of-concept case studies in patients with acute illness of unknown …

The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus
(EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore …

A 14-year-old boy with severe combined immunodeficiency presented three times to a
medical facility over a period of 4 months with fever and headache that progressed to …

The 2013–2016 epidemic of Ebola virus disease in West Africa was of unprecedented
magnitude and changed our perspective on this lethal but sporadically emerging virus. This …

Bovine respiratory disease (BRD) is one of the most important diseases impacting the global
cattle industry, resulting in significant economic loss. Commonly referred to as shipping …

Next generation sequencing is in the process of evolving from a technology used for
research purposes to one which is applied in clinical diagnostics. Recently introduced high …