Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Cancer and oncologic therapies can have significant adverse effects on male reproductive
potential, leaving many men permanently infertile. Fertility preservation has emerged as a …

This research presents a novel testis-on-a-chip (ToC) platform. Testicular cells are
enzymatically isolated from the seminiferous tubules of sexually immature mice, seeded in a …

STUDY QUESTION Can transgender women cryopreserve germ cells obtained from their
orchiectomy specimen for fertility preservation, after having used puberty suppression and/or …

Patient survival following childhood cancer has increased with contemporary radiation and
chemotherapy techniques. However, gonadotoxicity associated with treatments means that …

Human male reproductive development has a prolonged prepubertal period characterized
by juvenile quiescence of germ cells with immature spermatogonial stem cell (SSC) …

The spermatogonial stem cell (SSC) is a unique adult stem cell that requires tight
physiological regulation during development and adulthood. As the foundation of …

Purpose As a secondary report to elucidate the diverse spectrum of oncofertility practices for
childhood cancer around the globe, we present and discuss the comparisons of oncofertility …

Genetic causes are thought to underlie about half of infertility cases, but understanding the
genetic bases has been a major challenge. Modern genomics tools allow more …

During the past decades, several endocrine disrupting chemicals (EDCs) have been
confirmed to affect male reproductive function and fertility in animal studies. EDCs are …