[PDF][PDF] Redox metabolism: ROS as specific molecular regulators of cell signaling and function

C Lennicke, HM Cochemé - Molecular Cell, 2021 - cell.com
Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

[PDF][PDF] NRF2 and the Hallmarks of Cancer

MR de la Vega, E Chapman, DD Zhang - Cancer cell, 2018 - cell.com
The transcription factor NRF2 is the master regulator of the cellular antioxidant response.
Though recognized originally as a target of chemopreventive compounds that help prevent …

The heat‐shock protein/chaperone network and multiple stress resistance

P Jacob, H Hirt, A Bendahmane - Plant biotechnology journal, 2017 - Wiley Online Library
Crop yield has been greatly enhanced during the last century. However, most elite cultivars
are adapted to temperate climates and are not well suited to more stressful conditions. In the …

Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

HA Elfawy, B Das - Life sciences, 2019 - Elsevier
Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …

Salt stress proteins in plants: An overview

HR Athar, F Zulfiqar, A Moosa, M Ashraf… - Frontiers in Plant …, 2022 - frontiersin.org
Salinity stress is considered the most devastating abiotic stress for crop productivity.
Accumulating different types of soluble proteins has evolved as a vital strategy that plays a …

Oxidative stress

H Sies, C Berndt, DP Jones - Annual review of biochemistry, 2017 - annualreviews.org
Oxidative stress is two sided: Whereas excessive oxidant challenge causes damage to
biomolecules, maintenance of a physiological level of oxidant challenge, termed oxidative …

Linking oxidative stress and proteinopathy in Alzheimer's disease

C Sharma, SR Kim - Antioxidants, 2021 - mdpi.com
Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer's disease and Parkinson's disease

G Ganguly, S Chakrabarti, U Chatterjee… - Drug design …, 2017 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases
of the elderly people that have devastating effects in terms of morbidity and mortality. The …

Mitochondrial homeostasis and cellular senescence

PVS Vasileiou, K Evangelou, K Vlasis, MI Panayiotidis… - Cells, 2019 - mdpi.com
Cellular senescence refers to a stress response aiming to preserve cellular and, therefore,
organismal homeostasis. Importantly, deregulation of mitochondrial homeostatic …

Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis

JT Marinko, H Huang, WD Penn, JA Capra… - Chemical …, 2019 - ACS Publications
Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …